Kaposi's sarcoma versus bacillary angiomatosis

Abstract

Persons with acquired immune deficiency syndrome (AIDS) are subject to a host of pathologic entities secondary to a depressed immune system. Kaposi's sarcoma frequently presents in this immunocompromised population and, therefore, diagnosis seems clinically straightforward. However, because of the prevalence of a strikingly similar infectious disease known as bacillary angiomatosis, skin biopsy of one or more lesions is crucial.

Surface enhanced Raman scattering for the multiplexed detection of pathogenic microorganisms: towards point-of-use applications

“… 75 Rapid and effective clinical diagnosis of the two diseases is essential for patients in these countries because they have similar histopathological features and clinical presentations. 76 The SERS tags were prepared by functionalising gold NPs with a Raman reporter and DNA probes complementary to part of the target viral DNA strands, which in this example were synthesised as oligonucleotide fragments. The LFA strips consisted of two streptavidin-biotinylated capture probes for KSHV and BA targets and a control line containing a DNA chain complementary to the spacer region on the DNA probes of both SERS tags.…”

Newly diagnosed AIDS with neurosyphilis, Kaposi sarcoma, pancytopenia, oropharyngeal candidiasis, and pseudomonal pneumonia: We shouldn’t be seeing this anymore

“…Bartonella henselae , also the cause of “Cat Scratch Disease” [ 6 ]. It usually presents in either papular or nodular forms.…”

Multiplexed colorimetric detection of Kaposi's sarcoma associated herpesvirus and Bartonella DNA using gold and silver nanoparticles

“…13, 21 However, while these features are characteristic of KS, a number of other diseases, including bacillary angiomatosis (BA) caused by Bartonella henselae or quintana , and pyogenic granuloma with no known infectious cause, can often have a similar clinical and histological appearance and represent a diagnostic challenge. 18–19 …”