Kaposi's sarcoma

Dalgleish, A. G.

doi:10.1038/bjc.1991.229

Cited by 11 publications

(3 citation statements)

References 32 publications

(23 reference statements)

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“…The finding that HHV-8 is present in B-cell compartment and in neoplastic cells of primary effusion lymphomas suggests that it is a transmissible B-lymphotropic herpesvirus, probably originating from KS-endothelial cells or circulating HHV-8 infected spindle or endothelial cells (Cesarman et al, 1995;Whitby et al, 1995). Furthermore, lymphoma-like alterations have been described in lymph-nodes of KS patients, and there is evidence that the original KS cell resembles that of the lymphatic endothelium (Dalgleish, 1991). It is not clear whether lymphomas and KS share an alteration of the phenotype of the infected B-cell; however, KS have been found to be less frequently in individuals who contract HIV through blood transfusion (Beral et al, 1990); however, it was founded by others (Serraino et al, 1992).…”

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confidence: 93%

Classic Kaposi's sarcoma as a second primary neoplasm

et al. 1999

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confidence: 93%

Classic Kaposi's sarcoma as a second primary neoplasm

et al. 1999

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“…Kaposi's sarcoma is defined as an idiopathic multiple pigmented sarcoma and it was first described by Moritz Kaposi in 1872. 8 KS is currently categorized into four different types: classic, endemic, epidemic and post-transplant form. 9 The form of KS originally identified by Kaposi became known as classic KS or sporadic KS.…”

Section: Discussionmentioning

confidence: 99%

A rare case of bilateral conjunctival Kaposi's sarcoma in a HIV-negative patient

Fossataro

Iuliano

Uccello

et al. 2021

American Journal of Ophthalmology Case Reports

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Purpose Kaposi's sarcoma (KS) is a rare multi-centric vascular neoplasm, first described by Moritz Kaposi in 1872. It can appear in four different forms: classic, endemic, HIV-related and post-transplant form. We present an uncommon case of seronegative HIV infection patient with skin KS involving conjunctiva of both eyes. Observations Firstly, right eye lesions were surgically removed. Subsequently, the patient was administered with systemic chemotherapy (doxorubicin) to treat both skin and left eye lesions. No signs of recurrence were observed at 20 months’ follow-up. Conclusions Both eyes involvement in KS is rarely described in scientific literature. Both surgery and chemotherapy could be considered valid treatment options for conjunctival KS.

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“…It is commonly described in elderly people (both men and women) of Mediterranean origin. In addition, immunosuppression has been related to the development of the disease, since KD has been observed in patients receiving immunosuppressive therapy after organ transplantation [5], and it is frequently diagnosed in human immunodeficiency virus (HIV) antibody (Ab)-seropositive patients [6]. The neoplastic nature of KD is controversial [7][8][9][10][11]; hence, the entity has recently been designated "Kaposi's disease" [12,13].…”

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confidence: 99%