Kalp Damar Cerrahisine Bağlı Akut Böbrek Yaralanması

Abstract

Cardiopulmonary bypass (CPB) is an extracorporeal circulatory model consisting essentially of a pump, reservoir and oxygenator. At the beginning of CPB, blood of the patient flows into the extracorporeal circulation, which does not contain the endothelial surface, from the patient and initiates the inflammatory process, that is developed by the cellular, extracellular or humoral components of the blood and this process varies according to the patient's genotype, peroperative parameters and complexity of the pathology. Acute renal injury among patients undergoing cardiac surgery appears to be associated with poor prognosis and increased mortality. Acute kidney injury (AKI) is a condition that increases the common mortality and morbidity in intensive care unit (ICU) patients and adversely affects the clinical course.