2008
DOI: 10.2174/157017808785982284
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KAl(SO4)2.12H2O Supported on Silica gel Catalyzed Coupling of 4- Hydroxyproline with Isatins, 11H-Indeno[1,2-b]quinoxalin-11-ones, Quinones and 9H-Fluoren-9-one: An Efficient Synthesis of Some Interesting Pyrroles

Abstract: Abstracts: Some interesting pyrrole derivatives were synthesized in moderate to high yields by coupling of 4-hydroxyproline with isatins, 11H-indeno[1,2-b]quinoxalin-11-ones, quinones and 9H-fluoren-9-one, in the presence of catalytic amount of Alum supported on silica gel (Alum-SiO 2 ), under microwave irradiation.

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Cited by 4 publications
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“…Alum, well known for its traditional role in water treatments (coagulation and clarification) has recently been reported as a reusable, cheap and excellent catalyst for the preparation of organic compounds, for example, in the transesterification of palm oil [28], synthesis of -aminophosphonates [29], 2,3dihydroquinazolin-4(1H)-ones [30], 1,3,4-Oxadiazoles [31], di-hydropyrimidinones [32], cis-isoquinolonic acids [33], pyrroles [34] and coumarins [35]. Thus, continuing our research on new one-pot reactions, we considered Alum to be ideal for affecting the synthesis of mono-and bis-2amino-4H-pyrans via a three-or pseudo five-component reaction of 4-hydroxycoumarin, malononitrile and aldehydes in ethanol/water media at room temperature.…”
Section: Resultsmentioning
confidence: 99%
“…Alum, well known for its traditional role in water treatments (coagulation and clarification) has recently been reported as a reusable, cheap and excellent catalyst for the preparation of organic compounds, for example, in the transesterification of palm oil [28], synthesis of -aminophosphonates [29], 2,3dihydroquinazolin-4(1H)-ones [30], 1,3,4-Oxadiazoles [31], di-hydropyrimidinones [32], cis-isoquinolonic acids [33], pyrroles [34] and coumarins [35]. Thus, continuing our research on new one-pot reactions, we considered Alum to be ideal for affecting the synthesis of mono-and bis-2amino-4H-pyrans via a three-or pseudo five-component reaction of 4-hydroxycoumarin, malononitrile and aldehydes in ethanol/water media at room temperature.…”
Section: Resultsmentioning
confidence: 99%