“…The lignans from this family are commonly classified into five classes, i.e., dibenzocyclooctadiene, spirobenzofuranoid dibenzocyclooctadiene, 1,4-diarylbutane, 4-aryltetralin, and diaryltetrahydrofuran [1]. Recent pharmacological studies have revealed that these compounds accounted for anti-oxidant [2,3], anti-HIV [4,5], antihepatitis B virus [6], and anti-proliferative multiple bio-effects [7]. In addition, schisantherin A (2) has been reported to exhibit anti-inflammatory properties by down-regulating NF-kappaB and MAPK signaling pathways in lipopolysaccharide-treated RAW 264.7 cells [8].…”