Juxtaglomerular Cell Tumor: A Rare Presentation of a Surgically Curable Cause of Secondary Hypertension in the Pediatric Population

Phillis, Corey; Midenberg, Eric; O'Connor, Matthews; Terry, William J.; Keel, Christopher; Noh, Paul H.

doi:10.1016/j.urology.2021.05.030

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2024

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“…Hypokalaemia is, however, not always present, and occurs in approximately 80% of the cases 2 . Although reninomas are most commonly diagnosed during the third and fourth decades of life, 2 children with reninomas have been described 3,4 . There is a gender bias, with a female‐to‐male ratio of 2:1 2,5,6 .…”

Section: Introductionmentioning

confidence: 99%

Diagnostic challenges in patients with reninomas and extrarenal renin‐producing tumours

Fabian,

Ragnarsson,

Prazic

et al. 2024

Clinical Endocrinology

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Renin‐secreting tumours are rare causes of secondary hypertension and hypokalaemia. They are usually surgically curable, hence proper diagnostic work‐up and tumour localisation is essential. In this paper, we present three Swedish patients recently diagnosed with renin secreting tumours, two with reninomas and one with an extrarenal renin‐producing tumour, to illustrate diagnostic challenges. We also discuss the biochemical work‐up, the pros and cons of different imaging techniques (computer tomography [CT], magnetic resonance imaging and [18F]fluorodeoxyglucose‐positron emission tomography‐CT), as well as how renal vein sampling (RVC) may contribute to localisation of the tumour.

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