Juxta-adrenal schwannoma presenting as a giant adrenal tumor: A case report and a literature review

Abdessater, Maher; Mokdad, Mohammad El; Gas, J.; Sleiman, Walid; Coloby, P.; Bart, S.

doi:10.1016/j.ijscr.2018.10.017

Cited by 15 publications

(14 citation statements)

References 22 publications

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“…Malignant schwannomas have a poor prognosis and a high recurrence rate, so early diagnosis is important while emphasizing the necessity of close postoperative follow-up ( 29 ). We should know that regardless of the nature of the tumor, the difficulty of surgery is closely related to the size of the mass and adjacent adhesions, so the importance of early surgery is emphasized instead of only considering the surgical technique ( 30 ). Our study confirmed that benign tumors with large size and adjacent complex vessels can still be completely resected with a satisfactory prognosis.…”

Section: Discussionmentioning

confidence: 99%

Clinical Characteristics and Treatment Strategy of Retroperitoneal Schwannoma Adjacent to Important Abdominal Vessels: Three Case Reports and Literature Review

Liu

Lü

et al. 2021

Front. Surg.

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Purpose: The purpose of this study was to review the clinical characteristics and treatment strategies of patients with retroperitoneal schwannomas adjacent to important abdominal vessels.Case Presentation: A total of three patients with retroperitoneal schwannoma immediately adjacent to important blood vessels in the abdominal cavity underwent successful surgical resection. They all had symptoms of abdominal pain and discomfort, two cases underwent three-dimensional reconstruction. There were no serious complications such as peripheral blood vessels and organ damage in all three cases. One case had chyle leakage after surgery, conservative treatment was successfully discharged.Conclusions: Retroperitoneal schwannomas immediately adjacent to important abdominal vessels have unique clinical characteristics. Preoperative three-dimensional reconstruction can fully show the local vascular relationship of the tumor, which is conducive to surgical planning and risk assessment. Benign tumors with large size and adjacent complex vessels can still be completely resected by surgery. Laparotomy resection is safe and feasible.

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Section: Discussionmentioning

confidence: 99%

Clinical Characteristics and Treatment Strategy of Retroperitoneal Schwannoma Adjacent to Important Abdominal Vessels: Three Case Reports and Literature Review

Liu

Lü

et al. 2021

Front. Surg.

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“…AS is a rare incidentaloma found in the adrenal medulla, and fewer than 100 cases have been reported to date (10,6,(11)(12)(13)(14)(15)(16)(17)(18). The vast majority of AS patients are sporadic.…”

Section: Discussionmentioning

confidence: 99%

Clinical features and outcomes of adrenal schwannoma: a study of 13 cases from a single centre

Henghai¹,

Ding

Lin³

et al. 2021

Endocrine Connections

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Background: Adrenal schwannomas (AS) are extremely rare neoplasms. This study shares our experience regarding the diagnosis and operative management of AS. Methods: Clinical details, radiologic, laboratory, and pathologic findings as well as follow-up data were analyzed retrospectively for 13 AS patients who accepted surgery at a tertiary referral hospital in China between January 1, 1996, and December 31, 2017. Results: The mean age of the patients at diagnosis was 44.7 ± 13.7 years (range 19–62 years; male: female ratio, 1:1.16), of whom 7 patients had unilateral AS on the right side, and the remaining 6 on the left side. None of the cases were hormonally active. None of the 13 cases were diagnosed as AS by computed tomography imaging before the operation. Among the patients, 10 were asymptomatic. The mean preoperative size was 7.1 ± 3.2 cm (range 1.6–12.6 cm). All patients underwent surgery, with open adrenalectomy in 5 patients and laparoscopy in 8 patients. The mean tumor size on pathologic examination was 6.8 ± 3.0 cm (range 3.0–11.7 cm). The surgical specimens were confirmed by pathological examination. During a median follow-up of 60.8 ± 17.7 months, no patients showed recurrence or metastasis. Conclusion: The preoperative diagnosis of AS remains difficult despite the advances in imaging examinations. After complete resection, the prognosis of AS is excellent.

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“…Standard management of adrenal schwannomas is surgical resection as they are not sensitive to radiotherapy and chemotherapy [4]. e appropriate approach in adrenal schwannomas, either laparoscopic or open, remains debatable.…”

Section: Discussionmentioning

confidence: 99%

“…Surgery is the treatment of choice, whenever feasible. Consequently, a definitive diagnosis can only be made upon histological and immunohistochemical studies of the resected lesion [4]. Herein, we report a case of large adrenal schwannoma mimicking adrenal adenoma with a brief review of the literature.…”

Section: Introductionmentioning

confidence: 99%

Schwannoma Misdiagnosed as Adrenal Adenoma: A Case Report and Review of the Literature

Almalki

Alotaibi

Ahmad

et al. 2020

Case Reports in Endocrinology

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Schwannoma is a benign neurogenic tumor originating from the neural sheath of Schwann cells. It is an extremely rare cause of adrenal adenoma which is very difficult to diagnose preoperatively. We report the case of a right adrenal schwannoma discovered incidentally in a 62-year-old woman during evaluation of right flank pain. The biochemical and hormonal evaluations were unremarkable. Radiological examination revealed a 4.8 cm lesion keeping with right adrenal adenoma. Surgical intervention was done due to the large size of the tumor, and laparoscopic right adrenalectomy was performed. The postoperative course was uneventful. Histological examination established the diagnosis of schwannoma, which was further confirmed by immunohistochemical staining. In conclusion, adrenal schwannoma is extremely rare and can be misdiagnosed as nonsecreting adrenal adenoma. Complete surgical excision is the treatment of choice which is associated with favorable outcome and also helps in clarifying its histopathological nature.

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Juxta-adrenal schwannoma presenting as a giant adrenal tumor: A case report and a literature review

Cited by 15 publications

References 22 publications

Clinical Characteristics and Treatment Strategy of Retroperitoneal Schwannoma Adjacent to Important Abdominal Vessels: Three Case Reports and Literature Review

Clinical Characteristics and Treatment Strategy of Retroperitoneal Schwannoma Adjacent to Important Abdominal Vessels: Three Case Reports and Literature Review

Clinical features and outcomes of adrenal schwannoma: a study of 13 cases from a single centre

Schwannoma Misdiagnosed as Adrenal Adenoma: A Case Report and Review of the Literature

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