“… 9 Although it remains unclear how and whether cortical activity differences may contribute to the observed visual stimulus orienting responses, Shank3 knockout mice also fail to execute normal continuous prey pursuits. 37 Shank3 knockout mice are impaired in classical forms of visual cortex plasticity, 27 although SC function and plasticity were not analyzed. It will therefore be important in future work to study the coordinated development of cortical and SC circuits as related to binocular visual processing during this behavior.…”