Juvenile recurrent respiratory papillomatosis in pregnancy: a case report

Abstract

Juvenile-onset recurrent respiratory papillomatosis (JORRP) is a rare disease, usually acquired by vertical transmission upon vaginal delivery. Human Papilloma Virus (HPV) is the etiologic agent and the most common types involved are 6 and 11 that are the same types associated with anogenital condylomas. It is associated with low mortality but with significant morbidity. Pregnancy was related with accelerated papilloma growth in RRP, while RRP may have an effect on the outcome of pregnancy due to chronic maternal hypoxemia. We present a case of Juvenile onset recurrent respiratory papilloma in pregnancy seen starting 7 weeks age of gestation. The effect of pregnancy on JORRP, its effect on pregnancy, and the latest modalities in treatment including the role of HPV vaccination are discussed in the article with the review of literature.