Juvenile recurrent respiratory papillomatosis: 10‐year audit and Australian prevalence estimates

Novakovic, Daniel; Cheng, Alan; Baguley, Katherine; Walker, Paul; Harrison, Henley C.; Soma, Marlene; Malloy, Michael J.; Brotherton, Julia

doi:10.1002/lary.26005

Cited by 24 publications

(13 citation statements)

References 31 publications

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“…Whereas 4vHPV vaccination has consistently been successful in reducing HPV 6/11/16/18 infection and disease, reported estimates of impact vary widely. In addition to the actual effectiveness of the vaccine itself, assessment of population impact depends on multiple factors including the breadth of the immunization program (cohort and catch-up), completeness and accuracy of data sources, availability and utilization of screening programs, the outcome under study, and vaccine coverage in females and males [ 26 – 30 ] [ Supplementary Table 3 ]. Vaccine coverage may in turn be affected by national priorities and funding, access to healthcare, civil unrest, sexual practices, and vaccine acceptance.…”

Section: Discussionmentioning

confidence: 99%

Impact and Effectiveness of the Quadrivalent Human Papillomavirus Vaccine: A Systematic Review of 10 Years of Real-world Experience

Garland¹,

Kjær²,

Muñóz³

et al. 2016

Clin Infect Dis.

393

289

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Section: Discussionmentioning

confidence: 99%

Impact and Effectiveness of the Quadrivalent Human Papillomavirus Vaccine: A Systematic Review of 10 Years of Real-world Experience

Garland¹,

Kjær²,

Muñóz³

et al. 2016

Clin Infect Dis.

393

289

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“…Convincing data on respiratory papillomatosis (RRP) are available from Australia 32 . Between 2011 and 2015, pediatricians and otolaryngologists collected data of newly diagnosed cases of juvenile RRP and published them in a meeting report.…”

Section: Epidemiologymentioning

confidence: 99%

“…Aus Australien liegen überzeugende Daten zur respiratorischen Papillomatose (RRP) vor 32 . Von Pädiatern und HNO-Ärzten wurden zwischen 2011 und 2015 neu aufgetretene Fälle juveniler RRP gesammelt und in einem Kongreßbericht publiziert.…”

Section: 4 Entwicklung In Regionen Mit Konsequenter Primärprophylaxeunclassified

HPV – Das andere Kopf-Hals-Karzinom

et al. 2018

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Head and neck cancer is the sixth most common cancer with over 500000 annually reported incident cases worldwide. Besides major risk factors tobacco and alcohol, oropharyngeal squamous cell carcinomas (OSCC) show increased association with human papillomavirus (HPV). HPV-associated and HPV-negative OSCC are 2 different entities regarding biological characteristics, therapeutic response, and patient prognosis. In HPV OSCC, viral oncoprotein activity, as well as genetic (mutations and chromosomal aberrations) and epigenetic alterations plays a key role during carcinogenesis. Based on improved treatment response, the introduction of therapy de-intensification and targeted therapy is discussed for patients with HPV OSCC. A promising targeted therapy concept is immunotherapy. The use of checkpoint inhibitors (e.g. anti-PD1) is currently investigated. By means of liquid biopsies, biomarkers such as viral DNA or tumor mutations in the will soon be available for disease monitoring, as well as detection of treatment failure. By now, primary prophylaxis of HPV OSCC can be achieved by vaccination of girls and boys.

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“…Children may thus also present with recurrent pneumonia, bronchiectasis, and declining pulmonary status 2 . In Australia between 2000 and 2013, the estimated prevalence of respiratory papillomatosis was 0.81 per 100 000 among children aged < 15 years, peaking at age 5 to 9 years (1.1 per 100 000), 4 and is expected to decline with broader HPV vaccine coverage.…”

Section: Introductionmentioning

confidence: 99%

Absence of human papillomavirus in nasopharyngeal swabs from infants in a population at high risk of human papillomavirus infection

Smith‐Vaughan

Cheng

Tabrizi

et al. 2021

Pediatric Investigation

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Maternal urogenital human papillomavirus (HPV) infection may place neonates at risk of HPV acquisition and subsequently lower respiratory infections as HPV can influence development of immunity. The respiratory HPV prevalence is not known in remote‐dwelling Aboriginal infants, who are at high risk of respiratory infection and where the population prevalence of urogenital HPV in women is high. These data are necessary to inform HPV vaccination regimens. A retrospective analysis using PCR specific for HPV was performed on 64 stored nasopharyngeal swabs from remote‐dwelling Aboriginal infants < 6 months of age, with and without hospitalised pneumonia. HPV DNA was not detected in any specimen. Despite the negative result, we cannot exclude a role for HPV in respiratory infections affecting infants in this population; however, our data do not support HPV as an important contributor to acute respiratory infection in remote‐dwelling Aboriginal children.

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Juvenile recurrent respiratory papillomatosis: 10‐year audit and Australian prevalence estimates

Abstract: 4 Laryngoscope, 126:2827-2832, 2016.

Cited by 24 publications

References 31 publications

Impact and Effectiveness of the Quadrivalent Human Papillomavirus Vaccine: A Systematic Review of 10 Years of Real-world Experience

Impact and Effectiveness of the Quadrivalent Human Papillomavirus Vaccine: A Systematic Review of 10 Years of Real-world Experience

HPV – Das andere Kopf-Hals-Karzinom

Absence of human papillomavirus in nasopharyngeal swabs from infants in a population at high risk of human papillomavirus infection

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