Juvenile ossifying fibroma: An unusual case report and review of the literature

Ossifying Fibroma of Nasal Cavity: A Rare Case Report

“…Such lesions may contain trabecular of lamellar bone rimmed by osteoblasts with numerous small rounded psammoma like bodies present in the cellular tissue in 60 % of cases [1,6]. WHO (World Health Organization) new classification has a new term as JOF (Juvenile Ossifying Fibroma) to those fast-growing mass between 5-15 years of age with well bordered on radiology with consistency of ossifying fibroma on histology [7,8]. JOF has two histological variants: Juvenile psammomata ossifying fibroma and juvenile trabecular.…”

“…The psammomata type is more common than the trabecular variety, is more aggressive, and possess high recurrence tendency. It has characteristics of a well-defined, unilocular or multilocular expansile and well-circumscribed radiolucent lesions with cortical thinning radiologically [7][8][9]. It may invade the eye socket, skull base and calvarium and may present with related symptoms, and its malignancy rate is (0.4-0.5%).…”

“…The closest condition that needs to be differentiated is from fibrous dysplasia and the differentiating features being fast growing lesion, monostatic nature and the well delineated radiographic margins [10]. Other differential diagnosis includes osteoblastoma, osteosarcoma, eventifying fibroma, and aneurysmal bone cyst [7]. The only effective treatment for such lesion is the complete resection [4] and there are many approaches for the access.…”