Juvenile myoclonic epilepsy and narcolepsy: A series of three cases

Joshi, Puja; Poduri, Annapurna; Kothare, Sanjeev V.

doi:10.1016/j.yebeh.2015.07.030

Cited by 9 publications

(2 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The prevalence of sleepwalking and sleep paralysis is as high as 15.3% and 11.7% in a cohort of patients with genetic generalized epilepsy and their relatives, respectively, implying a shared genetic pathway [ 27 ]. A three-case series of the coexistence of juvenile myoclonic epilepsy and narcolepsy indicated shared genetic predisposition of HLA-DQB1*0602 between these two diseases; however, more evidences are required to demonstrate it [ 28 ]. The prevalence of restless leg syndrome (RLS) was between 18-35% and periodic limb movement disorder (PLMD) was 5% among patients with epilepsy who were referred to a sleep lab [ 15 ].…”

Section: Sleep Disorders In Patients With Epilepsymentioning

confidence: 99%

The Management and Alternative Therapies for Comorbid Sleep Disorders in Epilepsy

Peng

Ding

Wang

2021

View full text Add to dashboard Cite

Background: There is a complex and interactive relationship between sleep and epilepsy. Sleep disorders are common in patients with epilepsy, and methods for managing sleep disorders in patients with epilepsy are limited. Objective: This review is to address the relationships among sleep, sleep disorders, and epilepsy, focusing on the managements for sleep disorders in epilepsy, including some complementary and alternative therapies. Methods: The terms related to “sleep” and “epilepsy” were searched in “Pubmed” and “Cochrane Library”. Results: Sleep stages differently affects both of seizures and interictal epileptiform discharges. Seizures disrupt sleep architectures greatly, especially when arising from sleep in the night. Insomnia and obstructive sleep apnea (OSA) are the most frequent types of comorbid sleep disorders in patients with epilepsy. Pharmacological agents with both anti-convulsant and sedative effects are the priorities for comorbid sleep disorders in epilepsy. Continuous positive airway pressure (CPAP) therapy is the most effective non-pharmacological method to improve OSA and reduce seizures. Complementary and alternative therapies such as Chinese traditional medicine, cognitive behavioral therapy, meditation, yoga, neurofeedback, and acupuncture may have benefits on reducing seizures and improving sleep quality simultaneously by alleviating stress and seizure triggers, however, evidence-based therapies are still in deficiency. Conclusion: Managements for sleep disorders in patients with epilepsy are challenging. Large sample randomized controlled trials are in demand in the future.

show abstract

Section: Sleep Disorders In Patients With Epilepsymentioning

confidence: 99%

The Management and Alternative Therapies for Comorbid Sleep Disorders in Epilepsy

Peng

Ding

Wang

2021

View full text Add to dashboard Cite

show abstract

“…Another study demonstrated 11.1% of PWE had excessive daytime sleepiness, more frequently in the presence of obstructive sleep apnea and depression [49]. Although excessive daytime sleepiness is frequently reported, comorbid narcolepsy and epilepsy has been infrequently documented with only a few recent case series published [50,51].…”

Section: Hypersomnia and Narcolepsymentioning

confidence: 99%

Sleep Disorders in Epilepsy: Current Trends and Future Perspectives

Grayson

DeWolfe

2018

Curr Sleep Medicine Rep

View full text Add to dashboard Cite

Purpose of Review Sleep complaints are common in people with epilepsy (PWE). We aim to highlight the updated evidence regarding comorbid sleep disorders and epilepsy and the impact of epilepsy and its treatments on sleep. Recent Findings Up to two thirds of PWE report sleep disturbances which may signal presence of a comorbid sleep disorder, including insomnia, arousal parasomnias, excessive daytime sleepiness, obstructive sleep apnea, or restless legs syndrome. Uncontrolled seizures contribute to poor sleep quality, while presence of epilepsy (with or without seizures) and antiepileptic drugs is associated with changes in sleep architecture. Chronic intracranial EEG monitoring with implanted devices reveals a nocturnal peak for interictal epileptiform activity. Epilepsy surgery outcomes suggest better seizure control may improve sleep architecture and quality. Summary Screening for and treating sleep disorders may lead to improved seizure control and quality of life in PWE. Epilepsy surgery and implanted devices to treat refractory epilepsy provide new insights into the relationship between sleep and epilepsy.

show abstract

Epilepsy and Sleep in Adolescents

Jain

Kothare

2016

Sleep Disorders in Adolescents

View full text Add to dashboard Cite

Juvenile myoclonic epilepsy and narcolepsy: A series of three cases

Cited by 9 publications

References 21 publications

The Management and Alternative Therapies for Comorbid Sleep Disorders in Epilepsy

The Management and Alternative Therapies for Comorbid Sleep Disorders in Epilepsy

Sleep Disorders in Epilepsy: Current Trends and Future Perspectives

Epilepsy and Sleep in Adolescents

Contact Info

Product

Resources

About