Juvenile Hyaline Fibromatosis A Case Report of A Localized Form?

Differential glycosaminoglycan expression and hyaluronan homeostasis in juvenile hyaline fibromatosis

“…Furthermore, it has been shown that abnormal collagen metabolism is a distinct feature of JHF lesions. These studies have shown a defect in type III, 25 type IV, 5,27 and type VI 26,28 collagen. It has been suggested that the abnormal formation of collagen fibers results from an underlying defect in GAG synthesis.…”

Infantile systemic hyalinosis: Report of two severe cases from Saudi Arabia and review of the literature

“…Other authors reported perianal nodules/papules but our cases had marked large sized nodules (16,17). The perianal nodule, although it is highly characteristic of ISH, might be misdiagnosed as condylomata which herein has been ruled out by a negative test for human papilloma virus (18).…”

Juvenile Hyaline Fibromatosis

“…Two separate forms of the disease have been proposed: a localized form that's characterized by very slow growth of lesions and a diffuse form that's characterized by large and rapidly growing tumors (5). The case presented here was the diffuse type and this is the first reported case of the diffuse type of JHF in Korea.…”