Juvenile Angiofibroma: Evolution of Management

Nicolai, Piero; Schreiber, Alberto; Villaret, Andrea Bolzoni

doi:10.1155/2012/412545

Cited by 77 publications

(119 citation statements)

References 90 publications

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“…About 96% of JNA arises from the pterygopalatine fossa with the lesion showing homogenous enhancement post contrast. 4 A study by Atalar 1 in a group of 72 patients showed three characteristic, consistent findings that suggest a diagnosis of JNA. These are: 1.…”

Section: Discussionmentioning

confidence: 91%

“…Biopsy of JNA can result in massive hemorrhage, hence should be avoided. 2,4 Histopathologically, features of vascularity and fibroblasts are seen. Fibroblasts are plump, ovoid to spindle shaped, with excessive amount of connective tissue.…”

Section: Discussionmentioning

confidence: 99%

“…Advanced lesions may show cranial nerve involvement. 2,4 Diagnosis should ideally be aided by contrast enhanced computed tomography (CT) to recognize the origin, extensions as well as pattern of vascularity of the lesion. About 96% of JNA arises from the pterygopalatine fossa with the lesion showing homogenous enhancement post contrast.…”

Section: Discussionmentioning

confidence: 99%

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Multidetector Computed Tomography Evaluation of Juvenile Nasopharyngeal Angiofibroma

Somayaji¹,

Talwade²,

Shukla³

et al. 2016

The Journal of Medical Sciences

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Juvenile nasopharyngeal angiofibroma is relatively uncommon accounting for 0.5% of all head and neck tumors occurring exclusively in adolescent males. It is a microscopically benign, yet locally aggressive tumor with high rates of recurrence and results in severe morbidity. Diagnosis requires high index of suspicion as it mimics other sinonasal conditions, like sinonasal polyp, neurofibroma, nasopharyngeal carcinoma, etc. A case of 14-year-old boy with history of swelling in the right cheek, bilateral nasal obstruction, epistaxis, and watering from right eye referred for multidetector computed tomography is reported in this study. Source of support: Nil Conflict of interest: None INTRODUCTIONJuvenile nasopharyngeal angiofibroma (JNA) is a benign, vascular, and fibrous neoplasm arising in the nasopharynx accounting for 0.5% of all head and neck tumors. It almost always occurs exclusively in adolescent males. The tumor exhibits a strong tendency to bleed and frequently exhibits destructive and aggressive behavior.1,2 It wasHippocrates who first described it in the 5th century bc. However, Friedberg first used the term angiofibroma in 1940. The diagnosis of this condition requires a high index of suspicion as it mimics other sinonasal conditions and approaching it as such may result in fatal outcome. 2 We present a case of JNA and discuss the steps necessary for radiological diagnosis using multidetector computed tomography (MDCT). CASE REPORTA 14-year-old boy presented with complaints of swelling in right cheek since 1 month, which progressively increased in size (Fig. 1). Patient also complained of bilateral nasal obstruction with history of 3 to 4 episodes of epistaxis in the last month. Patient gave history of watering from right eye. On examination, right nasal cavity showed an ulcerative growth with dilated blood vessels and serosanguinous discharge along with a swelling involving the right buccal mucosa extending to the soft and hard palate (Fig. 2)

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Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Multidetector Computed Tomography Evaluation of Juvenile Nasopharyngeal Angiofibroma

Somayaji¹,

Talwade²,

Shukla³

et al. 2016

The Journal of Medical Sciences

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“…Intracranial extension is noted in 10-20 % of cases. Different staging systems based on tumor extension have been proposed [ 30 ].…”

Section: Angiofi Broma Disease Pathophysiologymentioning

confidence: 99%

Skull Base Tumors

Sweeney¹,

Gückenberger²

2015

Principles and Practice of Stereotactic Radiosurgery

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“…Only about fifteen cases of the angiofibroma in adolescent females were described. The incidence of the JNA is less than 0.5% of tumors arising in the head and neck [3]. In USA this lesion is the most frequent head and neck tumor of the adolescence with 1 new case per 5000 to 50000 patients referred to otolaryngologist [4].…”

Section: Introductionmentioning

confidence: 99%

Juvenile Angiofibroma Occurring in an Unusual Site: Report of a Case

Niedzielski¹

2015

Pediat Therapeut

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Extra Nosopharyngeal Angiofibromas (ENA) is a tumor of fibrotic and angiovascular consistency which are localized outside the nasopharyngx (i.e. nasal septum). The clinical characteristic of ENA and JNA (juvenile angiofiborma) is not conclusive and the diagnosis of the ENA is problematic. The nine year old girl was administered to the Children Otolaryngology Clinic. The histopathological examination proved that the removed mass was angiofibroma. According to literature and our clinical experience it is important to be aware of the atypical localization of the juvenile angiofibromas. According to literature only about 15 cases of the similar case were reported.

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Juvenile Angiofibroma: Evolution of Management

Cited by 77 publications

References 90 publications

Multidetector Computed Tomography Evaluation of Juvenile Nasopharyngeal Angiofibroma

Multidetector Computed Tomography Evaluation of Juvenile Nasopharyngeal Angiofibroma

Skull Base Tumors

Juvenile Angiofibroma Occurring in an Unusual Site: Report of a Case

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