There is considerable literature on the relative advantages and disadvantages of e-cigarettes/electronic nicotine delivery systems (hence ''e-cigarettes'') [1−4]. Proponents have argued that e-cigarettes are a safer alternative to traditional smoked tobacco [5]. Conversely, opponents have argued that they can encourage nonsmokers to begin smoking tobacco and/or expose nonsmokers (and potentially, those nearby) to the risks associated with inhaling e-cigarette vapour, with uncertain long-term consequences [6−8]. The first argument-that e-cigarettes can promote smoking cessation-positions these devices as a quitting aid. This approach corresponds with marketing e-cigarettes as relatively more advantageous than smoked tobacco due to lower health risks. The argument also implies that e-cigarettes should be marketed with information on how users can decrease nicotine intake over time to facilitate nicotine withdrawal, devoid of glamourised promotion. Conversely, marketing e-cigarettes with glamour, youthful images, and reference to multiple flavours weakens their position as a quitting aid and strengthens their position as a lifestyle device. This approach potentially increases the interest of nonsmokers and/or young people, who are likely to be exposed to the risks associated with e-cigarettes, without benefiting from reduced tobacco-smoking. Consistent with the different potential methods of marketing e-cigarettes discussed above, how e-cigarettes are marketed is likely to change their relative risks and benefits. If e-cigarettes are marketed as a lifestyle device, with the potential to attract the interest of nonsmokers and/or young people, the associated risks are likely to increase. Conversely, if e-cigarettes are largely marketed as a quitting aid, this can minimise the associated risks by not encouraging their use among nonsmokers. Among e-cigarettes, JUUL recently achieved prominence due to its rapid increase in market share, high-levels of brand recognition and use among adolescents [9]. With only moderate marketing expenditure, JUUL was transformed from a littleknown brand to the largest retail e-cigarette brand in the United States. This followed innovative, engaging, and widereaching campaigns on Twitter, Instagram, and YouTube [10]. The rapid growth of JUUL, largely due to social media promotion, makes JUUL particularly problematic, since non-smoking adolescents who use JUUL or other e-cigarettes would be exposed to the associated risks, without any benefit from reduced tobacco-smoking.