Jurisdictional Procedure

Abstract

Scholars have lavished attention on the substance of jurisdictional

Burkholderia as a Source of Natural Products

“…Although several reviews have been published on specific aspects of Burkholderia natural products, such as natural products discovered via genome mining, 5 siderophores and lipopeptides, 52 nonribosomal peptides and polyketides, 53 antibiotics from neglected bacteria, 3 and antibiotics from Gram-negative bacteria, 54 a comprehensive account of Burholderia as a source of natural products is outstanding. In order to compile information regarding compounds isolated, their reported bioactivities, and the method of isolation, we searched Web of Science and SciFinder using following search terms "[Burkholderia or Paraburkholderia or Caballeronia or Robbsia] and [natural product or secondary metabolite or isolated compound]".…”

“…As more Burkholderia genomes become available, there has been a collective realization that this bacterial group is a promising and relatively untapped source of natural products with therapeutic and biotechnological relevance. 3,5,9,[52][53][54] The number of putative natural product BGCs varies depending on the species and their ecological niches and do not necessarily correlate with genome size. For example, an antiSMASH 223 (genome size of 9.7 Mb) yielded only ten putative BGCs, that is 1.0 BGC per Mb (Figure 4).…”