Journey of a Late Blooming Biochemical Neuroscientist

Vesicular and Plasma Membrane Transporters for Neurotransmitters

“…Cite this article as Cold Spring Harb Perspect Biol 2012;4:a005595 highly sensitive fluorescence and radiotracer flux assays for epinephrine, norepinephrine (NE), DA and 5-HT enabled Julius Axelrod and his colleagues to identify reuptake as the major mechanism that terminates synaptic transmission (Axelrod 2003). In particular, the group showed that the actions of multiple psychotropic drugs, including cocaine and tricyclic antidepressants, derive from their inhibition of biogenic amine reuptake (Whitby et al 1960;Hertting et al 1961;Glowinski and Axelrod 1964).…”

Reaction Paths in the Respiration of the Higher Plants

“…Subsequent efforts to improve techniques have also met with many troubles, and methods that have proved satisfactory with animal tissues have sometimes given disappointing results with plants (12).…”

A Brief History of Great Discoveries in Pharmacology: In Celebration of the Centennial Anniversary of the Founding of the American Society of Pharmacology and Experimental Therapeutics

“…So, by 1955, at the rather advanced age of 42, Julius Axelrod had earned a doctoral degree and was now in a position to set up an independent research program (Axelrod, 2003). Because of his extensive experience working at Goldwater Memorial Hospital and then at the Laboratory of Chemical Pharmacology at the NIH, Axelrod soon was appointed Chief of the Section of Pharmacology at the National Institute of Mental Health.…”