Journal of Clinical Monitoring and Computing 2015 end of year summary: tissue oxygenation and microcirculation

Scheeren, Thomas

doi:10.1007/s10877-016-9846-4

Cited by 19 publications

(15 citation statements)

References 32 publications

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“…Initially, near-infrared spectroscopy (NIRS) was used to measure regional brain oxygen saturation; recently, NIRS has also been used to monitor peripheral tissue oxygen saturation (StO 2 ) and microvascular reactivity using the vascular occlusion test (VOT) [1,2]. Many studies on StO 2 changes during the VOT also deal with other concepts such as association with flow-mediated dilatation [3], strategies to protect from prolonged forearm ischemia [4], and differences in vascular function between the DOI: 10.1159/000510072 trained and untrained limbs [5].…”

Section: Introductionmentioning

confidence: 99%

“…INVOS ® (Somanetics Corp., Troy, MI, USA) was developed for measuring regional brain oxygen saturation through the use of 2 light-emitting diodes [13], and IN-VOS ® has also been widely used to obtain tissue oxygen saturation in areas other than the brain and peripheral microcircular reactivity measurements using VOT [1,2,14]. O3 TM (Massimo Corp., Irvine, CA, USA) is a recently developed NIRS method that uses 4 wavelengths, and only a few studies have used this device to measure cerebral oxygen saturation [15] or StO 2 [16].…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of Different Near-Infrared Spectroscopy Devices for Assessing Tissue Oxygenation with a Vascular Occlusion Test in Healthy Volunteers

Chung

Jang

et al. 2020

J Vasc Res

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Near-infrared spectroscopy devices can measure peripheral tissue oxygen saturation (StO 2). This study aims to compare StO 2 using INVOS ® and different O3™ settings (O3 25:75 and O3 30:70). Twenty adults were recruited. INVOS ® and O3™ probes were placed simultaneously on 1 side of forearm. After baseline measurement, the vascular occlusion test was initiated. The baseline value, rate of deoxygenation and reoxygenation, minimum and peak StO 2 , and time from cuff release to peak value were measured. The parameters were compared using ANOVA and Kruskal-Wallis tests. Bonferroni's correction and Mann-Whitney pairwise comparison were used for post hoc analysis. The agreement between StO 2 of devices was evaluated using Bland-Altman plots. IN-VOS ® baseline value was higher (79.7 ± 6.4%) than that of O3 25:75 and O3 30:70 (62.4 ± 6.0% and 63.7 ± 5.5%, respectively, p < 0.001). The deoxygenation rate was higher with IN-VOS ® (10.6 ± 2.1%/min) than with O3 25:75 and O3 30:70 (8.4 ± 2.2%/min, p = 0.006 and 7.5 ± 2.1%/min, p < 0.001). The minimum and peak StO 2 were higher with INVOS ®. No significant difference in the reoxygenation rate was found between the devices and settings. The time to reach peak after cuff deflation was faster with INVOS ® (both p < 0.001). Other parameters were similar. There were no differences between the different O3™ settings. There were differences in StO 2 measurements between the devices, and these devices should not be interchanged. Differences were not observed between O3™ device settings.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Evaluation of Different Near-Infrared Spectroscopy Devices for Assessing Tissue Oxygenation with a Vascular Occlusion Test in Healthy Volunteers

Chung

Jang

et al. 2020

J Vasc Res

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“…Early resuscitation of microcirculation is associated with reduced multiorgan failure and SOFA score. [ 36 49 50 ] Microcirculatory alterations have previously been proved to have prognostic value independently with respect to morbidity and mortality in septic shock. [ 17 51 52 53 ] In our study, peripheral and sublingual perfusions have close associations with prognosis and provide a feasible view and experimental data for a microcirculation resuscitation endpoint.…”

Section: Discussionmentioning

confidence: 99%

Role of Combining Peripheral with Sublingual Perfusion on Evaluating Microcirculation and Predicting Prognosis in Patients with Septic Shock

Pan

Liu

et al. 2018

Chinese Medical Journal

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Background:Measurement of general microcirculation remains difficult in septic shock patients. The peripheral perfusion index (PI) and sublingual microcirculation monitoring are thought to be possible methods. This study was performed to determine whether assessing microcirculation by PI and a new parameter, proportion of perfusion vessel change rate (ΔPPV) from sublingual microcirculation monitoring, can be associated with patients' outcome.Methods:A prospective observational study was carried out, including 74 patients with septic shock in a mixed intensive care unit. Systemic hemodynamic variables were obtained at T0 and 6 h after (T6). PI and sublingual microcirculation indicators were obtained using a bedside monitor and a sidestream dark-field device, respectively. The t-test, analysis of variance, Mann-Whitney U-test, Kruskal-Wallis test, receiver operating characteristic curve analysis with the Hanley-McNeil test, survival curves using the Kaplan-Meier method, and the log-rank (Mantel-Cox) test were used to statistical analysis.Results:Systemic hemodynamics and microcirculation data were obtained and analyzed. Patients were divided into two groups based on whether the first 6 h lactate clearance (LC) was ≥20%; PI and ΔPPV were lower at T6 in the LC <20% group compared with LC ≥20% (PI: 1.52 [0.89, 1.98] vs. 0.79 [0.44, 1,81], Z = −2.514, P = 0.012; ΔPPV: 5.9 ± 15.2 vs. 17.9 ± 20.0, t = −2.914, P = 0.005). The cutoff values of PI and ΔPPV were 1.41% and 12.1%, respectively. The cutoff value of the combined indicators was 1.379 according to logistic regression. Area under the curve demonstrated 0.709 (P < 0.05), and the sensitivity and specificity of using combined indicators were 0.622 and 0.757, respectively. Based on the PI and ΔPPV cutoff, all the participants were divided into the following groups: (1) high PI and high ΔPPV group, (2) high PI and low ΔPPV group, (3) low PI and high ΔPPV group, and (4) low PI and low ΔPPV group. The highest Sequential Organ Failure Assessment score (14.5 ± 2.9) was in the low PI and low ΔPPV group (F = 13.7, P < 0.001). Post hoc tests showed significant differences in 28-day survival rates among these four groups (log rank [Mantel-Cox], 20.931; P < 0.05).Conclusion:PI and ΔPPV in septic shock patients are related to 6 h LC, and combining these two parameters to assess microcirculation can predict organ dysfunction and 28-day mortality in patients with septic shock.

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“…A recent published review by Ekbal et al [9] summarizes the additional monitoring tools that may provide, in real time, early warning signals on tissue perfusion and metabolism in critically ill patients. In 2016, Scheeren [10] presented a list of new technologies that will enable the clinician to monitor and evaluate the microcirculation and tissue oxygenation in addition to the macro-circulation and respiratory function available today.…”

Section: Introductionmentioning

confidence: 99%

Perioperative Cardiovascular Evaluation of Patients Oxygen Balance and Tissue Metabolic Score (TMS)

Mayevsky¹,

Tolmasov²,

Mandelbaum³

2018

AJCTS

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During the perioperative period of cardiovascular surgeries an imbalance between oxygen supply and demand may lead to postoperative cognitive decline that may affect about 20% of the operated patients. In order to minimize the development of brain damage, few companies had developed monitoring devices that could provide real-time information regarding brain oxygenation, brain electrical activities or cerebral blood flow. Nevertheless this approach is not the appropriate way to detect an early warning signal that may serve as an indicator of brain negative oxygen balance. The alternative approach is to monitor tissue oxygen balance of one of the less vital organ in the body that may serve as an early warning signal of deterioration of body oxygen balance. In this review, the use of a multiparametric monitoring device (CritiView) connected to the patient's urethral wall via a 3-way Foley catheter that measure in real time 4 parameters representing tissue oxygen balance. Mitochondrial NADH is measured by surface fluorometry/reflectometry. In addition, tissue microcirculatory blood flow, tissue reflectance and hemoglobin oxygenation are measured as well. The measured 4 parameters could be integrated together with systemic hemodynamic parameters to provide in real time a new Tissue Metabolic Score (TMS). The device was tested both in vitro and in vivo in a small animal model and in preliminary clinical trials in patients undergoing vascular or open heart surgery. In patients, the monitoring started immediately after the insertion of a 3-way Foley catheter (urine collection) to the patient and was stopped when the patient was discharged from the operation room. The results show that monitoring the Urethral wall oxygen balance provides information in correlation to the surgical procedure performed.

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Journal of Clinical Monitoring and Computing 2015 end of year summary: tissue oxygenation and microcirculation

Cited by 19 publications

References 32 publications

Evaluation of Different Near-Infrared Spectroscopy Devices for Assessing Tissue Oxygenation with a Vascular Occlusion Test in Healthy Volunteers

Evaluation of Different Near-Infrared Spectroscopy Devices for Assessing Tissue Oxygenation with a Vascular Occlusion Test in Healthy Volunteers

Role of Combining Peripheral with Sublingual Perfusion on Evaluating Microcirculation and Predicting Prognosis in Patients with Septic Shock

Perioperative Cardiovascular Evaluation of Patients Oxygen Balance and Tissue Metabolic Score (TMS)

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