Joint estimation of water/fat images and field inhomogeneity map

Hernando, Diego; Haldar, Justin P.; Sutton, Bradley P.; Ma, Jingfei; Kellman, Peter; Liang, Zhi‐Pei

doi:10.1002/mrm.21522

Cited by 176 publications

(286 citation statements)

References 23 publications

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“…In spite of his good performances in terms of SNR, this algorithm assumes very low B0 inhomogeneities and converges to local minimum when this condition is not verified which resulted also in a bad fat and water separation. Many solutions were proposed to tackle this problem (Hernando et al 2008;Hernando et al 2010;Sharma et al 2012), but all of them work only for 2D images with a high computation time and they are not available on clinical machines. Furthermore, in the case of our application, the fat content is very low compared to the water one which means that the impact of the selection of echo time on the SNR is minor as shown in (Reeder et al 2005).…”

Section: Discussionmentioning

confidence: 99%

NMR imaging estimates of muscle volume and intramuscular fat infiltration in the thigh: variations with muscle, gender, and age

Hogrel

Barnouin

Azzabou

et al. 2015

AGE

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Muscle mass is particularly relevant to follow during aging, owing to its link with physical performance and autonomy. The objectives of this work were to assess muscle volume (MV) and intramuscular fat (IMF) for all the muscles of the thigh in a large population of young and elderly healthy individuals using magnetic resonance imaging (MRI) to test the effect of gender and age on MV and IMF and to determine the best representative slice for the estimation of MV and IMF. The study enrolled 105 healthy young (range 20-30 years) and older (range 70-80 years) subjects. MRI scans were acquired along the femur length using a three-dimension three-point Dixon proton density-weighted gradient echo sequence. MV and IMF were estimated from all the slices. The effects of age and gender on MV and IMF were assessed. Predictive equations for MV and IMF were established using a single slice at various femur levels for each muscle in order to reduce the analysis process. MV was decreased with aging in both genders, particularly in the quadriceps femoris. IMF was largely increased with aging in men and, to a lesser extent, in women. Percentages of MV decrease and IMF increase with aging varied according to the muscle. Predictive equations to predict MV and IMF from single slices are provided and were validated. This study is the first one to provide muscle volume and intramuscular fat infiltration in all the muscles of the thigh in a large population of young and elderly healthy subjects.

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Section: Discussionmentioning

confidence: 99%

NMR imaging estimates of muscle volume and intramuscular fat infiltration in the thigh: variations with muscle, gender, and age

Hogrel

Barnouin

Azzabou

et al. 2015

AGE

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“…Author Manuscript (17) where . Note that for arbitrary k-space trajectories, the Gram matrix , or the coefficient matrix of (17), has a block Toeplitz structure [25].…”

Section: Algorithmmentioning

confidence: 99%

Maximum likelihood reconstruction for magnetic resonance fingerprinting

Zhao

Lam

Bilgic̦

et al. 2015

2015 IEEE 12th International Symposium on Biomedical Imaging (ISBI)

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This paper introduces a statistical estimation framework for magnetic resonance (MR) fingerprinting, a recently proposed quantitative imaging paradigm. Within this framework, we present a maximum likelihood (ML) formalism to estimate multiple parameter maps directly from highly undersampled, noisy k-space data. A novel algorithm, based on variable splitting, the alternating direction method of multipliers, and the variable projection method, is developed to solve the resulting optimization problem. Representative results from both simulations and in vivo experiments demonstrate that the proposed approach yields significantly improved accuracy in parameter estimation, compared to the conventional MR fingerprinting reconstruction. Moreover, Personal use of this material is permitted. However, permission to use this material for any other purposes must be obtained from the IEEE by sending a request to pubs-permissions@ieee.org. HHS Public Access Author Manuscript Author ManuscriptAuthor ManuscriptAuthor Manuscript the proposed framework provides new theoretical insights into the conventional approach. We show analytically that the conventional approach is an approximation to the ML reconstruction; more precisely, it is exactly equivalent to the first iteration of the proposed algorithm for the ML reconstruction, provided that a gridding reconstruction is used as an initialization.

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“…A 24-gauge angiocatheter was used to cannulate the portal vein. Once access was obtained, method was used for the current study (22). These VARPRO-based methods involve jointly solving for both chemical shift signal components and field inhomogeneities; VARPRO permits the use of both single-and multipeak chemical shift signal models (22,23).…”

Section: Animal Model Preparationmentioning

confidence: 99%

Chemical Shift MR Imaging Methods for the Quantification of Transcatheter Lipiodol Delivery to the Liver: Preclinical Feasibility Studies in a Rodent Model

Yin¹,

Guo²,

Li³

et al. 2012

Radiology

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Purpose:To demonstrate the feasibility of using chemical shift magnetic resonance (MR) imaging fat-water separation methods for quantitative estimation of transcatheter lipiodol delivery to liver tissues. Materials and Methods:Studies were performed in accordance with institutional Animal Care and Use Committee guidelines. Proton nuclear MR spectroscopy was first performed to identify lipiodol spectral peaks and relative amplitudes. Next, phantoms were constructed with increasing lipiodol-water volume fractions. A multiecho chemical shift-based fatwater separation method was used to quantify lipiodol concentration within each phantom. Six rats served as controls; 18 rats underwent catheterization with digital subtraction angiography guidance for intraportal infusion of a 15%, 30%, or 50% by volume lipiodol-saline mixture. MR imaging measurements were used to quantify lipiodol delivery to each rat liver. Lipiodol concentration maps were reconstructed by using both single-peak and multipeak chemical shift models. Intraclass and Spearman correlation coefficients were calculated for statistical comparison of MR imaging-based lipiodol concentration and volume measurements to reference standards (known lipiodol phantom compositions and the infused lipiodol dose during rat studies). Results:Both single-peak and multipeak measurements were well correlated to phantom lipiodol concentrations (r 2 . 0.99). Lipiodol volume measurements were progressively and significantly higher when comparing between animals receiving different doses (P , .05 for each comparison). MR imaging-based lipiodol volume measurements strongly correlated with infused dose (intraclass correlation coefficients . 0.93, P , .001) with both single-and multipeak approaches. Conclusion:Chemical shift MR imaging fat-water separation methods can be used for quantitative measurements of lipiodol delivery to liver tissues.q RSNA, 2012

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Joint estimation of water/fat images and field inhomogeneity map

Cited by 176 publications

References 23 publications

NMR imaging estimates of muscle volume and intramuscular fat infiltration in the thigh: variations with muscle, gender, and age

NMR imaging estimates of muscle volume and intramuscular fat infiltration in the thigh: variations with muscle, gender, and age

Maximum likelihood reconstruction for magnetic resonance fingerprinting

Chemical Shift MR Imaging Methods for the Quantification of Transcatheter Lipiodol Delivery to the Liver: Preclinical Feasibility Studies in a Rodent Model

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