Joint coordinate system for biomechanical analysis of the sacroiliac joint

Hauwermeiren, L. Van; Verstraete, Matthias; Stouthandel, Michael E. J.; Oevelen, Aline Van; Gersem, Werner De; Delrue, Louke; Achten, Eric; Adriaens, Dominique; Hoof, Tom Van

doi:10.1002/jor.24271

Cited by 4 publications

(4 citation statements)

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“…The SIJ is an auricular shaped joint known to transfer forces between the lumbar spine and lower limbs. The auricular joint surface connects sacral and the iliac bones and is surrounded by strong ligaments [1,2]. Functionally speaking, the SIJ is a joint with limited motion capabilities.…”

Section: Introductionmentioning

confidence: 99%

Comparative Study of Imaging and Pathology of Sacroiliac Joint in Normal Rats Based on IVIM-DWI and DCE-MRI

Qin¹,

Yao²,

Zhu³

et al. 2020

Preprint

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Background : There are few reports describing the relationship between functional MRI findings and pathology of normal sacroiliac joint (SIJ). Furthermore, the pathology of SIJ is difficult to access, so animal models have special value. Aims:We undertook this study to explore the changes of parameters of Intravoxel Incoherent Motion Diffusion Weighted Imaging(IVIM-DWI), Dynamic Contrast Enhanced Magnetic Resonance Imaging(DCE-MRI) and compare them with pathology in the SIJ of normal rats in different ages.Methods: Thirty 7 week-old male wistar rats were included in the study. The parameters of IVIM-DWI and DCE-MRI in bone marrow and the joint space of SIJ were measured respectively at 8, 13, 18, 23, 28 and 33 weeks, then histological specimen of the SIJ were examined with light microscopy. One-way ANOVA were used for statistical analysis. Results: The values of D in the sacral and iliac bone marrow of normal rats in different age groups decreased with the increase of age, and ANOVA indicated a significant difference in D values among different age groups(P＜0.005). The normal values of D*, f, Fenh(%), Senh(%/s) in the sacral bone marrow, the iliac bone marrow and in the joint space in SIJ of normal rats were obtained. In six groups of rats with different weeks of age, the pathology of the SIJ surface was smooth and clear, the cartilage cells were intact, and no thickening or pannus formation was found. Conclusions: The range of IVIM-DWI and DCE-MRI parameters of the sacral and iliac bone marrow and of the synovial area of the joint space in normal rats were obtained. It provides a basis for further clinical study of SIJ lesions.

show abstract

Section: Introductionmentioning

confidence: 99%

Comparative Study of Imaging and Pathology of Sacroiliac Joint in Normal Rats Based on IVIM-DWI and DCE-MRI

Qin¹,

Yao²,

Zhu³

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…The SIJ is an auricular shaped joint known to transfer weight and forces between the lumbar spine and lower limbs. The auricular joint surface connects the sacral and the iliac bones and it is surrounded by strong ligaments [1,2]. Considering its functional ability, the SIJ has limited motion capabilities.…”

Section: Introductionmentioning

confidence: 99%

Comparative study of imaging and histology of sacroiliac joint in normal rats based on IVIM-DWI and DCE-MRI

Qin

Yao

et al. 2020

BMC Musculoskelet Disord

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Background: Currently, few studies have described the relationship between functional MRI findings and histology of normal sacroiliac joint (SIJ). Besides, due to the difficulties in access to SIJ, authentic animal models are important in providing opportunities for quantitative parameter extraction on imaging. Aims: This study aimed at exploring the parameters of Intravoxel Incoherent Motion Diffusion-Weighted Imaging (IVIM-DWI) and Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) and comparing them with the histology of the SIJ in normal rats with different ages. Methods: A total of thirty 7-week-old male Wistar rats were included in the study. The parameters of IVIM-DWI and DCE-MRI in the bone marrow and the joint space of SIJ were measured at 8, 13, 18, 23, 28, and 33 weeks. The histological analysis of the SIJ was examined using light microscopy. One-way ANOVA was used for statistical analysis. Results: The D values in the sacral and iliac bone marrow of normal rats decreased with an increase in age. One-way ANOVA analysis indicated a significant difference in D values in different age groups (P<0.005). The normal values of D*, f, Fenh (%), Senh (%/s) in the sacral bone marrow, the iliac bone marrow, and the joint space in SIJ of normal rats were obtained. The results showed that in the six groups of rats of different ages, the histology of the SIJ surface was smooth and clear, the cartilage cells were intact, and no thickening or pannus formation was observed. Conclusions: This study obtained the IVIM-DWI and DCE-MRI parameters of the sacral and iliac bone marrow and the synovial area of the joint space in normal rats. The parameters in normal rats can be used in future research to compare to similar parameters in animal models or patients with SIJ diseases. This study serves as a guide for future research in SIJ diseases.

show abstract

“…The auricular joint surface connects sacral and the iliac bones and is surrounded by strong ligaments [1,2]. Functionally speaking, the SIJ is a joint with limited motion capabilities.…”

Section: Introductionmentioning

confidence: 99%

Comparative Study of Imaging and Histology of Sacroiliac Joint in Normal Rats Based on IVIM-DWI and DCE-MRI

Qin¹,

Yao²,

Zhu³

et al. 2020

Preprint

View full text Add to dashboard Cite

Background : There are few reports describing the relationship between functional MRI findings and histology of normal sacroiliac joint (SIJ). Furthermore, the histology of SIJ is difficult to access, so animal models have special value. Aims:We undertook this study to explore the changes of parameters of Intravoxel Incoherent Motion Diffusion Weighted Imaging(IVIM-DWI), Dynamic Contrast Enhanced Magnetic Resonance Imaging(DCE-MRI) and compare them with histology in the SIJ of normal rats in different ages.Methods: Thirty 7 week-old male wistar rats were included in the study. The parameters of IVIM-DWI and DCE-MRI in bone marrow and the joint space of SIJ were measured respectively at 8, 13, 18, 23, 28 and 33 weeks, then histological specimen of the SIJ were examined with light microscopy. One-way ANOVA were used for statistical analysis. Results: The values of D in the sacral and iliac bone marrow of normal rats in different age groups decreased with the increase of age, and ANOVA indicated a significant difference in D values among different age groups(P＜0.005). The normal values of D*, f, Fenh(%), Senh(%/s) in the sacral bone marrow, the iliac bone marrow and in the joint space in SIJ of normal rats were obtained. In six groups of rats with different weeks of age, the histology of the SIJ surface was smooth and clear, the cartilage cells were intact, and no thickening or pannus formation was found. Conclusions: The range of IVIM-DWI and DCE-MRI parameters of the sacral and iliac bone marrow and of the synovial area of the joint space in normal rats were obtained. These parameters in normal rats can be used in future research to compare them to the same parameters in animal models or patients with SIJ diseases.This study can be a guide for future research in SIJ diseases.

show abstract

Joint coordinate system for biomechanical analysis of the sacroiliac joint

Cited by 4 publications

References 40 publications

Comparative Study of Imaging and Pathology of Sacroiliac Joint in Normal Rats Based on IVIM-DWI and DCE-MRI

Comparative Study of Imaging and Pathology of Sacroiliac Joint in Normal Rats Based on IVIM-DWI and DCE-MRI

Comparative study of imaging and histology of sacroiliac joint in normal rats based on IVIM-DWI and DCE-MRI

Comparative Study of Imaging and Histology of Sacroiliac Joint in Normal Rats Based on IVIM-DWI and DCE-MRI

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