Johne's disease

The transmission and impact of paratuberculosis infection in domestic and wild ruminants

“…In 1895, Johne and Frothingham described the Pavlík et al, 1994bPavlík et al, , 2000a Germany Von Weber and Gürke, 1992a Review Article presence of acid fast bacilli in the intestine of a cow (Johne and Frothingham, 1895). In 1906 John M'Fadyean, suggested the disease be called Johne's disease (M'Fadyean et al, 1912). Twort and Ingram (1912), isolated the causative agent and named it as M. enteritis chronicae pseudotuberulosae bovis johne.…”

Mycobactin, a growth factor for Mycobacterium johnei. 1. Isolation from Mycobacterium phlei

“…Of these the first two were regarded as the best sources, and bovine and avian strains of Myco. tuberculos8i were said to be much inferior to human strains; this distinction was not confirmed by McFadyean, Sheather & Edwards (1912). None ofthe organisms, however, produced detectable amounts of the growth factor when grown on glycerol-liver broth, and,except with humanstrains, production ofgrowth factor was low or absent on egg medium.…”