This article examines some of the ways in which our experiences of, and interactions with, new technologies are grounded in the strategies and metaphors of reciprocity that govern everyday social life.Though I follow others in arguing that technology and society cannot be separated, I explore this interrelationship intersubjectively, looking first at some of the ways in which people relate to computers, then analysing the experiences of transplant recipients. I summarize my findings as a critique of the view that anthropomorphism is a quintessentially pre-modern phenomenon, and as a challenge to the idea that innovations in gene technology and cyber-technology presage a universal and inevitable dissolution of the boundaries between nature and culture, humans and machines.Most current debates about new technologies attempt to decide whether the innovations are good or bad, or how they may be regulated. The discourse is thus either ethical or governmental. But in focusing on how the effects of new technologies may be evaluated and managed, these debates often leave unexplored the more immediately empirical issue of how we actually experience and interact with technologies, and how our attitudes towards them are linked to perennial human anxieties about the strange, the new, and the other. My thesis in this article is an existential one. I take it as axiomatic that all human beings need to have a hand in choosing their lives, and to be recognized as having an active part to play in the shaping of their social worlds. As a corollary, I approach the meaning of what people say and do in terms of the degree to which they accomplish a balance between controlling their own fate, collective or otherwise, and accepting that which cannot be decided by human will or subjected to human designs. To define meanings without reference to this intersubjective dynamic is, in my view, practically meaningless.Thus, an anthropology of 'human-machine interaction' is unedifying while it insists that human intersubjectivity is reducible to cognitive schemata and communicative 'rationality' (e.g. Suchman 1987: 1).Over the last twenty years, several scholars have demonstrated that technology and society are intimately interconnected. Inspired by Heidegger's famous 1954 lecture on technology, Ihde's seminal Technics and praxis (1979) argued that '[h]uman-machine relations are existential relations in which our fate and destiny are implicated, but which are subject to the very ambiguity