With the destructive COVID-19 issues in China, the problem of job satisfaction has influenced more and more people, especially fresh graduates. Although existing research has discovered the association between job satisfaction and psychological distress, this study made contributions to the knowledge base and future researchers by investigating the mediation effect of coping on the above relationship. Fresh Graduates (N=384) completed questionnaires namely the Minnesota Satisfaction Questionnaire Short Form, the 4-item Brief Resilient Coping Scale, and The 10-item Kessler Psychological Distress Scale. Results showed there is a negative relationship between job satisfaction and psychological distress, and coping would partially mediate the above relationship. It was seen that job satisfaction is related with higher coping, while individuals with lower coping are more likely to experience higher levels of psychological distress, which may have a negative impact on their mental health and well-being. This study provides knowledge implications for society, policymakers, employers, and universities to be aware of the significance of fostering job satisfaction and promoting healthy coping strategies in order to improve the well-being of fresh graduates entering the workforce during difficult periods.