“…Indeed, jaundice has been reported to be a symptom during the course of the disease in 3 Á 13% of patients [6,7]. Hepatic dysfunction most often occurs as a result of intrahepatic involvement of HL (61%) [7], but also may be the result of extrahepatic bile duct obstruction, hemolysis, infectious hepatitis, or a toxic reaction to treatment such as chemotherapy or radiation therapy.…”