Jaundice

Two Cases of Untoward Reaction after"Ilosone"

“…A delay in onset of jaundice, such as occurred in Case 1, has also been noted with chlorpromazine jaundice (Sherlock, 1962). Prior to the introduction of this estolate of erythromycin there had been no reports of hepatic dysfunction associated with the drug.…”

Effect of Cooling on Pre-mixed Gas Mixtures for Obstetric Analgesia

“…A delay in onset of jaundice, such as occurred in Case 1, has also been noted with chlorpromazine jaundice (Sherlock, 1962).…”

Liver Function after Long-term Progestational Treatment with and Without Oestrogen

“…Y., 1964, 2, 920-921 Several reports have appeared indicating that a number of therapeutically valuable steroids may alter the excretory function of the liver, as judged by the results of the so-called liverfunction tests and the (sporadic) occurrence of jaundice. The presence of an alkylated group at C17 has been incriminated with regard to the hepatic effects observed with compounds such as methyltestosterone, nctethandrolone (1 7a-ethyl-19nortestosterone), methyloestrenolone (1 7a-methyl-1 9-nortestosterone), and methandienone ( I-1 7a-methyltestosterone) (Sherlock, 1962). The particular importance of checking the possible hepatotoxicity of any steroidal product intended for long-term use as an oral contraceptive has been emphasized (Lancet, 1962).…”