Jasmine absolute (Jasminum grandiflora L.) and its mode of action on guinea‐pig ileum in vitro

Abstract

Jasmine (Jasminum grandiflorum L.) is used in aromatherapy as a holistic treatment for apathy, hysteria, uterine disorders and childbirth, muscle relaxation and coughs. Its stimulant nature, on inhalation, has been shown both in animals and man. Jasmine has a spasmolytic activity on guinea-pig ileum and rat uterus in vitro. The mechanism of action of the spasmolytic activity, studied in vitro using a guinea-pig ileum smooth muscle preparation, was postsynaptic and not atropine-like. The spasmolytic effect of jasmine absolute was most likely to be mediated through cAMP, and not through cGMP. The mode of action in vitro resembled that of geranium, lavender and peppermint oils. The contradictory effect in vitro and in vivo is probably due to the solely physiological effects of jasmine absolute in vitro (producing a relaxation) compared with that in vivo, where it has a strong psychological input, producing a stimulant effect in man and enhanced movement in animals.

Antiulcer and in vitro antioxidant activities of Jasminum grandiflorum L.

“…The leaves of this species have a distinction of being used in Indian folk medicine for treating ulcers. Literature suggests the use of this plant as a diuretic and spasmolytic agent, which is given during childbirth (Somanadhan et al, 1998;Lis-Balchin et al, 2002).…”

Pharmacognostical and Preliminary Phytochemical Screening of the Leaf Extract of <i>Jasminum</i> <i>auriculatum</i> Vahl

“…Some of characters which are studied includes surface appearance and texture, lamina Structure (Nayak BS et al, 2007) Shape of lamina, Margin, Apex, Base, Venation (Balchin L et al, 2002). The leaves were subjected to macroscopic studies which comprised of colour, odour, and appearance taste, smell followed by (Brain et al, 1975).…”

Methanolic extract of leaves of Jasminum grandiflorum Linn modulates oxidative stress and inflammatory mediators

“…The other phenolic compounds include 3,4-dihydroxy-b-methoxyphenethyl alcohol, 3,4-dihydroxyphenethyl alcohol, 3,4-dihydroxybenzoic acid (protocatechuic acid), 2-hydroxy-3 0 ,4 0 -dihydroxyacetophenone, oleanolic acid (Sadhu et al 2007). Its biological properties include its antioxidant, anti-ulcer (Umamaheswari et al 2007), chemopreventive, anti-lipid peroxidative (Kolanjiappan and Manoharan 2005), spasmolytic (Lis-Balchin et al 2002) and angiotensin converting enzyme (ACE) inhibitor properties (Brinda et al 1998).…”