1957
DOI: 10.3181/00379727-94-23011 View full text |Buy / Rent full text
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Abstract: 556JBE VIRUS IN TISSUE CULTURE ministered in stimulating or depressing dosage. I t was not possible to test the therapeutic efficacy of reserpine after serotonin administration, as the neurological symptoms induced by intra-arterially injected serotonin were of too short duration.SuInzIncIr?1. 1) Serotonin. administered into brain-tissue via an estravascular route. induces edema. possibly due to its musculotropic property. 2 ) Serotonin was confirmed to have a neurotropic action which appeared to be responsibl… Show more

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“…In cultures of contiguous L mouse cells, JE viruses isolated in mice from various natural sources did not cause cytopathic effects although cytonecrosis was seen in cultures of sparse, noncontiguous cells (Dubbs and Scherer, 1966). In most human epithelial cells from continuous lines only minimal or inconsistent CPE has been described for strains Nakayama and Taira in HeLa cells (Scherer and Syverton, 1954;Mason, 1956) and for strains M1/311 and M3/2204B in HeLa, human intestine, human skin and Chang's conjunctival cells (McCollum and Foley, 1957;Banta, 1958). This note records the development of variants of JE virus with enhanced cytopathic effects (CPE) for contiguous L mouse and Lass human epithelial cells.…”
Section: Introductionmentioning
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“…In cultures of contiguous L mouse cells, JE viruses isolated in mice from various natural sources did not cause cytopathic effects although cytonecrosis was seen in cultures of sparse, noncontiguous cells (Dubbs and Scherer, 1966). In most human epithelial cells from continuous lines only minimal or inconsistent CPE has been described for strains Nakayama and Taira in HeLa cells (Scherer and Syverton, 1954;Mason, 1956) and for strains M1/311 and M3/2204B in HeLa, human intestine, human skin and Chang's conjunctival cells (McCollum and Foley, 1957;Banta, 1958). This note records the development of variants of JE virus with enhanced cytopathic effects (CPE) for contiguous L mouse and Lass human epithelial cells.…”
Section: Introductionmentioning