Japanese B Encephalitis

Kumar, Anil; Gupta, Vineet Bhushan

doi:10.1016/s0976-0016(11)60522-x

Cited by 1 publication

(1 citation statement)

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“…[1] JE has many different manifestations, but it is commonly characterized by sudden fever, headache, vomiting, cognitive impairment, and disturbance of consciousness, which is sometimes accompanied by epilepsy, Parkinson's disease, and other symptoms; in severe cases, respiratory failure can also occur. [2] There are few reports available on JE combined with cerebral hemorrhage, among which many described JE combined with bilateral thalamus or basal ganglia hemorrhage, while JE combined with multiple lobar hemorrhages has never been reported. Here we report such a case we encountered recently, together with literature review.…”

Section: Introductionmentioning

confidence: 99%

Severe Japanese encephalitis with multiple intracranial hemorrhages

Feng¹,

Chen²,

Bi³

et al. 2019

Medicine

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Rationale:Intracranial hemorrhage occurs infrequently in Japanese encephalitis (JE), and even less frequently with hemorrhage occurring twice. In this report, we describe the clinical features and outcomes of a patient with confirmed JE combined with hemorrhage twice.Patient concerns:The patient, a 71-year-old Asian woman, was admitted to the hospital with symptoms of hemiplegia following fever and diarrhea. Soon her condition worsened and a decreased level of consciousness, respiratory failure, and paralysis of extremities occurred.The brain diffusion-weighted imaging sequence showed suspicious abnormal signals in bilateral thalami. Japanese encephalitis virus immunoglobulin M antibody was detected in her serum and cerebrospinal fluid samples, so the patient was diagnosed with JE. During treatment, her condition became aggravated and the brain computed tomography (CT) scan showed multiple lobar hemorrhages. One month later, the multiple lobar hemorrhages occurred again, as observed by a brain CT scan.Diagnosis:JE with multiple intracranial hemorrhages.Interventions:The patient was treated comprehensively, including surgery, lowering her intracranial pressure and ventilator-assisted breathing.Outcomes:One month later, the patient underwent another surgical procedure for intracranial hemorrhage and suffered a serious neurological disorder.Lessons:Severe intracranial hemorrhage may occur in elderly patients with JE, especially in those with poor vascular condition. Therefore, when treating such patients, great caution, as well as early detection and prevention, should be taken in case of the occurrence of severe intracranial hemorrhage.

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Section: Introductionmentioning

confidence: 99%