Japan Renal Biopsy Registry: the first nationwide, web-based, and prospective registry system of renal biopsies in Japan

Abstract

Background The Committee for the Standardization of Renal Pathological Diagnosis and the Working Group for Renal Biopsy Database of the Japanese Society of Nephrology started the first nationwide, web-based, and prospective registry system, the Japan Renal Biopsy Registry (J-RBR), to record the pathological, clinical, and laboratory data of renal biopsies in 2007. Methods The patient data including age, gender, laboratory data, and clinical and pathological diagnoses were recorded on the web page of the J-RBR, which utilizes the system of the

Japan Renal Biopsy Registry and Japan Kidney Disease Registry: Committee Report for 2009 and 2010

“…In the J-RBR, a clinical diagnosis of chronic nephritic syndrome was the most common, followed by nephrotic syndrome, in both total biopsies and native kidneys in 2009 and 2010, which was similar to the findings in 2007 and 2008 (Table 4) [1]. In native kidneys, more than half of the cases that were registered had chronic nephritic syndrome.…”

“…In the classification of the pathogenesis, IgAN was diagnosed most frequently (31.6 %), followed by primary glomerular disease other than IgAN (27.2 %) in native kidneys in both 2009 and 2010 (Table 6). Similar frequencies of IgAN, primary glomerular disease other than IgAN and diabetic nephropathy were observed in the combined data for 2007 and 2008 [1]. In the pathological diagnosis classified based on the histopathology in native kidney biopsies, mesangial proliferative glomerulonephritis was the most frequently observed disease, representing 42.5 % and 35.8 % of the cases in 2009 and 2010 (Table 7).…”

“…The J-KDR was started in 2009 and the number of participating facilities increased by 34 compared to 2008, reaching a total of 57 facilities in the J-RBR and 59 facilities in the J-KDR. The number of total renal biopsies increased to 3,336 in 2009, which was 1,754 more biopsies than in the previous year [1], and in 2010 it further increased to 4,106 in the J-RBR. The number of other cases (not in the J-RBR), which corresponds to the cases without renal biopsies but diagnosed by clinical findings, was 680 and 575 in 2009 and 2010, respectively.…”

“…Clinical or renal histopathological diagnosis and laboratory data Three classifications, including the clinical diagnosis, histological diagnosis based on the pathogenesis, and histological diagnosis based on a histopathological examination, were made for each case included in the J-RBR, as described previously [1]. Of these classifications, the clinical diagnosis alone was selected for the J-KDR.…”

“…The estimated glomerular filtration rate was calculated as described previously [3]. The frequency of the diseases are here described in general, but the clinical data were also analyzed separately for cases of IgAN, which is the most common renal disease in Japan [1,4,5].…”