Japan Pancreatic Cancer Registry; 30th Year Anniversary

Egawa, Shinichi; Toma, Hiroki; Ohigashi, Hajime; Okusaka, Takuji; Nakao, Akimasa; Hatori, Takashi; Maguchi, Hiroyuki; Yanagisawa, Akio; Tanaka, Masao

doi:10.1097/mpa.0b013e318258055c

Cited by 372 publications

(306 citation statements)

References 7 publications

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“…According to a recent JPCR by JPS, the 5‐year survival rate of cases with UICC Stage 0 is 85.8%, which is a satisfactory prognosis 3. However, it has been difficult to diagnose PCIS without the presence of a formed mass lesion by any imaging modalities.…”

Section: Diagnosis Of Pcismentioning

confidence: 99%

“…This is attributed to the difficulty of early diagnosis of PC 1, 2. According to the recent Japan Pancreatic Cancer Registry (JPCR) analyzed by Japan Pancreas Society (JPS), the 5‐year survival rate of cases with tumors ≤10 mm (TS1a) reached 80.4%, and the 5‐year survival rate of cases with Stage 0 reached 85.8% 3. These data suggest that early diagnosis should play an important role in improving the prognosis of PC.…”

Section: Introductionmentioning

confidence: 99%

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Early diagnosis of pancreatic cancer: Current trends and concerns

Hanada

Amano

Abe

2017

Annals of Gastroent Surgery

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Early detection of pancreatic cancer (PC) is essential for a better prognosis. Some recent studies have demonstrated that a slight dilatation of the main pancreatic duct (MPD) and small cystic lesions were detected initially in most cases diagnosed at an early stage. Detecting these abnormal findings in cases with high risk factors through an effective screening system including image diagnosis, some biological markers, or familial cancer registrations should contribute to early diagnosis of PC. It has been reported that endoscopic ultrasonography (EUS) is essential for detecting tumors <10 mm with a favorable prognosis. Additionally, EUS‐guided fine‐needle aspiration biopsy is useful for confirming final histological diagnosis. For the diagnosis of stage 0 PC, local irregular stenosis of MPD should be an important initial abnormal sign detected by EUS or magnetic resonance cholangiopancreatography. Cytodiagnosis multiple times using pancreatic juice obtained by endoscopic nasopancreatic drainage should be essential for the final diagnosis. Recently, activities of regional networks between specialist doctors in medical centers and general practitioners for early diagnosis of PC have been reported in Japan. In the future, these activities may play an important role in the early diagnosis of PC.

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Section: Diagnosis Of Pcismentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Early diagnosis of pancreatic cancer: Current trends and concerns

Hanada

Amano

Abe

2017

Annals of Gastroent Surgery

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“…It is well known that tumor size can be one of the prognostic factors to impact on oncologic outcome of resected pancreatic cancer. 12,[30][31][32] In the present study, MTV 2.5 also showed strong relationship with radiologic Figure 1(A)). Radiologic tumor size was found to be one of the prognostic factors to predict tumor recurrence in univariate analysis (<2.5 vs !2.5, median 17.5 vs 7.3 months, P ¼ 0.035).…”

Section: Discussionmentioning

confidence: 56%

Preoperative volume-based PET parameter MTV2.5 as a potential surrogate marker for tumor biology and recurrence in resected pancreatic cancer

et al. 2014

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“…The 5-year survival rate of pancreatic tumors 10 mm or less is 80% compared with 4% for advanced stage IV disease. 2 The ability to achieve diagnosis at an earlier stage with more sensitive detection of biomarkers and enhanced imaging should therefore have a positive impact on patient survival. Equally, resection margin status is a risk factor for local recurrence and this has an impact on survival for some types of cancer.…”

Section: How Will This Impact Clinical Care?mentioning

confidence: 99%