Japan Collaborative Cohort Study for Evaluation of Cancer Risk Sponsored by Monbusho(JACC Study).

Ohno, Yoshiyuki; Tamakoshi, Akiko

doi:10.2188/jea.11.144

Cited by 210 publications

(208 citation statements)

References 4 publications

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“…The subjects were asked to complete a self-administered questionnaire about past medical history, various life style factors and marital status as baseline information. The detailed design of the JACC study has been described previously (Ohno and Tamakoshi, 2001;Watanabe et al, 2005). During the approximately 10 years of follow-up through December 31, 1999, there were 550 deaths from liver cancer that were coded as C22 in the International Classification of Diseases and Related Health Problems, 10th Revision.…”

Section: Methodsmentioning

confidence: 99%

The effect of interaction between hepatitis C virus and cigarette smoking on the risk of hepatocellular carcinoma

et al. 2006

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We evaluated the interaction between hepatitis C virus (HCV) and cigarette smoking on death from hepatocellular cancer in The Japan Collaborative Cohort Study. The odds ratio of death from HCC for smoking was 9.60 (1. 50 -61.35) Many studies have reported that chronic hepatitis C virus (HCV) infection is a risk factor for hepatocellular carcinoma (HCC) (Mori et al, 2000;El-Serag, 2002;Sun et al, 2003;Ayoola and Gadour, 2004), HCV appearing to be more hepatocarcinogenic than hepatitis B virus (HBV) (Pang et al, 2005). While alcohol is a well established risk factor for HCC, there is evidence that cigarette smoking is also a risk factor (Mukaiya et al, 1998;Mizoue et al, 2000;Chen et al, 2003), though some studies reported no or an insignificant association (La Vecchia et al, 1988;Evans et al, 2002). Recently, an association between diabetes mellitus and HCC (or HCV) has been reported (Caronia et al, 1999;Toyoda et al, 2001). We evaluated the interaction between HCV infection and cigarette smoking by means of a nested case -control study from a large cohort. MATERIALS AND METHODSThe Japan Collaborative Cohort Study (JACC Study) for Evaluation of Cancer Risk sponsored by the Ministry of Education, Science, Sports and Culture of Japan (Monbusho) is a large prospective cohort study, which was mounted from 1988 to 1990 in 45 areas in Japan. The number of subjects is 110 792 (46 465 males and 64 327 females) who were 40 -79 years of age at the time of the baseline survey. Individual informed consent to participate in the study was obtained in 36 out of 45 areas . The subjects were asked to complete a self-administered questionnaire about past medical history, various life style factors and marital status as baseline information. The detailed design of the JACC study has been described previously (Ohno and Tamakoshi, 2001;Watanabe et al, 2005). During the approximately 10 years of follow-up through December 31, 1999, there were 550 deaths from liver cancer that were coded as C22 in the International Classification of Diseases and Related Health Problems, 10th Revision. Those survey participants who underwent healthscreening checks sponsored by municipalities were asked to donate blood samples during the same period as the questionnaire survey. Eventually, 39 242 subjects provided blood samples . Baseline serum samples had been collected 120 of the 550 subjects who died of liver cancer. As the control group, sera of 11 543 subjects from the same geographical areas as the 120 deaths also were screened for anti-HCV. Deaths (nine) coded as C22.9 (liver cancer not otherwise specified) were excluded from this analysis, while deaths (five) coded as C22.1 (intrahepatic cholangiocarcinoma and cholangiohepatoma; included among non-HCC deaths), leaving 106 deaths from HCC that were regarded as the end point of this analysis. The total subjects were 11 654 but as the sera of 34 cases and controls could not be screened because of insufficient serum volume, the sera of 11 620 subjects were screened for antibody to HCV (anti-HCV) an...

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Section: Methodsmentioning

confidence: 99%

The effect of interaction between hepatitis C virus and cigarette smoking on the risk of hepatocellular carcinoma

et al. 2006

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“…All data were taken from the Japan Collaborative Cohort (JACC) Study, the methods of which have been described in detail elsewhere (Ohno and Tamakoshi, 2001). Briefly, the original study population consisted of 110 792 Japanese adults aged 40 -79 years.…”

Section: Methodsmentioning

confidence: 99%

“…Registration of death is required under the Family Registration Law in Japan, which applies throughout the country. Incidences of cancer were confirmed using records from the population-based cancer registries, which were supplemented by a systematic review of death certificates (Ohno and Tamakoshi, 2001); in some areas, medical records were also reviewed in major local hospitals. The mortality-to-incidence ratio for colorectal cancer was 0.28 in the cohort covered by the cancer registries.…”

Section: Methodsmentioning

confidence: 99%

Bowel movement frequency and risk of colorectal cancer in a large cohort study of Japanese men and women

et al. 2004

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The relationship between bowel movement (BM) frequency and the risk of colorectal cancer was examined in a large cohort of 25 731 men and 37 198 women living in 24 communities in Japan. At enrolment, each participant completed a self-administrated questionnaire on BM frequency and laxative use. Incidence rate ratios (IRR) with 95% confidence intervals (CI) were estimated using Cox's proportional-hazard model. During the follow-up period (average length 7.6 years), 649 cases of colorectal cancer, including 429 cases of colon cancer, were identified. Among women, subjects who reported a BM every 2 -3 days had the lowest risk of developing colorectal (IRR ¼ 0.71, 95% CI ¼ 0.52 -0.97) and colon cancer (IRR ¼ 0.70, 95% CI ¼ 0.49 -1.00), whereas those reporting a BM every 6 days or less had an increased risk of developing colorectal (IRR ¼ 2.47, 95% CI ¼ 1.01 -6.01) and colon cancer (IRR ¼ 2.52, 95% CI ¼ 0.93 -6.82) compared with those reporting X1 BM per day. A similar, but nonsignificant, association between the frequency of BM and cancer risk was observed in men. There was no association between colorectal or colon cancer risk and laxative use. Regulating BM frequency might therefore have a role in the prevention of colorectal cancer.

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“…Study methods and ethical issues have been described in detail elsewhere. [17][18][19] Briefly, our study was initiated in 1988 and enrollment was continued until the end of 1990. Subjects were followed until the end of 1997 unless they had moved out or developed one of the prospectively defined endpoints (described below).…”

Section: Jacc Studymentioning

confidence: 99%

Family history and the risk of stomach cancer death in Japan: Differences by age and gender

Yatsuya

Toyoshima

Mizoue

et al. 2001

Intl Journal of Cancer

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Familial aggregation of stomach cancer has long been observed. The effect on disease risk of family history and its magnitude according to the type of affected relatives, however, is not well known. We conducted a prospective analysis using the JACC study (Japan Collaborative Cohort Study For Evaluation of Cancer Risk, sponsored by Monbusho) data. During the follow-up period, 662 stomach cancer deaths were documented. A positive history of stomach cancer in one or more first-degree relatives was associated with a significantly increased risk of death from the disease in both men (RR 1.60; 95% CI 1.11-2.31) and women (RR 2.47; 95% CI 1.50 -4.06). In the subanalysis stratified by age, the association between positive family history and stomach cancer was stronger in the age group from 40 -59 (RR 2.62; 95% CI 1.34 -5.11 for men and RR 5.88; 95% CI 2.70 -12.82 for women) than in the age group from 60 -79 (RR 1.31; 95% CI 0.84 -2.05 for men and RR 1.44; 95% CI 0.72-2.88 for women). In the age group from 40 -59, men with father's history and women with mother's and sister's history of the disease had a significantly increased risk (RR 3.14; 95% CI 1.51-6.55, RR 10.46; 95% CI 4.54 -24.12, RR 13.39; 95% CI 3.89 -46.12, respectively). When 2 or more family members were affected, the increment in the risk was prominent especially in women (RR 9.45; 95% CI 4.46 -20.05). These results suggest the existence of a certain subtype of stomach cancer that is inherited more often by women from one generation to the next in gender-influenced fashion. Any preventive strategy should take into account the degree of individual susceptibility.

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Japan Collaborative Cohort Study for Evaluation of Cancer Risk Sponsored by Monbusho(JACC Study).

Cited by 210 publications

References 4 publications

The effect of interaction between hepatitis C virus and cigarette smoking on the risk of hepatocellular carcinoma

The effect of interaction between hepatitis C virus and cigarette smoking on the risk of hepatocellular carcinoma

Bowel movement frequency and risk of colorectal cancer in a large cohort study of Japanese men and women

Family history and the risk of stomach cancer death in Japan: Differences by age and gender

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