Abstract:The imbalance between endogenous and exogenous healing
is the fundamental
reason for the poor tendon healing. In this study, a Janus patch was
developed to promote endogenous healing and inhibit exogenous healing,
leading to improved tendon repair. The upper layer of the patch is
a poly(dl-lactide-co-glycolide)/polycaprolactone
(PLGA/PCL) nanomembrane (PMCP-NM) modified with poly(2-methylacryloxyethyl
phosphocholine) (PMPC), which created a lubricated and antifouling
surface, preventing cell invasion and mecha… Show more
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