Janus-like polymer particles prepared via internal phase separation from emulsified polymer/oil droplets

Wang, Yi; Guo, Baohua; Xian, Wan; Xu, Jun; Wang, Xin; Zhang, Yinping

doi:10.1016/j.polymer.2009.03.061

Cited by 77 publications

(65 citation statements)

References 29 publications

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“…It is also important to know how the release profile will be affected by the change of layer configurations altered by viscosity tweaking. The novelty of this article lies in describing how viscosity of polymer matrix can guide to adopt a specific layer configuration dictated by thermodynamics (as estimated by spreading coefficient theory, not by kinetics. The model actives used in this work were benzoic acid as hydrophilic antibacterial and tocopherol as hydrophobic antioxidant.…”

Section: Introductionmentioning

confidence: 99%

New insight into the mechanism of formation of dual actives loaded multilayered polymeric particles and their application in food preservation

Biswal¹,

Saha²

2019

J of Applied Polymer Sci

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This study provides an insight about the mechanism of formation of tri‐layered (instead of bilayers) particles originated from two biodegradable polymers by emulsion solvent evaporation method. It was also demonstrated how layer configurations of tri‐layered particles composed of poly(l‐lactide) (PLLA) and poly(d,l‐lactide‐co‐glycolide) (PLGA), can be changed from kinetically trapped to thermodynamically favorable structures (dictated by spreading coefficient theory) by tweaking several solution parameters. Layer switching, core, and shell thickness manipulation can also be achieved. Interestingly, among the various configurations, tri‐layered particles made with PLGA of intermediate viscosity and PLLA of high viscosity were found to provide controlled and sustainable release profiles for dual actives such as antibacterial (benzoic acid) and antioxidant (tocopherol) with appreciably high release rates. The dual activity of these particles was tested by incorporating them in chicken broth medium and found to provide excellent antibacterial as well as antioxidant activity for extended period of time (>20 days). © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 48009.

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Section: Introductionmentioning

confidence: 99%

New insight into the mechanism of formation of dual actives loaded multilayered polymeric particles and their application in food preservation

Biswal¹,

Saha²

2019

J of Applied Polymer Sci

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“…This particular kind of particle was named "Janus particles" by de Gennes in 1991. Many techniques, including surface coating by vapor deposition of metal thin lms, 7-9 masking of a photoresist layer, 10 selfassembly of polymer, 11,12 photo-polymerization in a micro-uidic channel, 13 and Pickering emulsion method, 14 were established to fulll the synthesis. They would behave in ways which are quite different from molecular amphiphiles.…”

Section: Introductionmentioning

confidence: 99%

Exploration of selective decoration of Janus silica particles within polymeric patterned pore arrays

et al. 2016

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Janus particles, especially amphiphilic ones, are known to be highly active when involved in interfacial selfassembly processes. However, experimental reports on employing Janus particles as an interfacial stabilizer to establish functional structures are rather limited. In this paper, amphiphilic Janus silica particles were prepared by selective chemical treatment on the particle "colloidosomes". Different ways (decoration of Au nanoparticles, interfacial adsorption test) were used to confirm the acquirement of the Janus character of the particles. Upon successful synthesis of amphiphilic Janus particles, they were employed in the breath figures method for the first time. It turned out that by using the Janus particles, a regularly arranged pore array could be easily obtained. Characterization of the morphology of the patterned structure shows that Janus particles were densely located on the interior wall of the entire holes, forming finer particle arrays compared to the case of isotropic particles. The result indicates that Janus particles show optimized behavior when they are involved in the interfacial self-assembly processes.With further work, by choosing Janus particles with functional features, selective functionalization of porous films could be achieved with high efficiency and great ease using this method.

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“…Because there is a continuous loss of solvents from droplets to the continuous phase, this system is far from thermal equilibrium. 51,52,54 We also demonstrated that one compartment of these Janus particles can be removed selectively to create bowlshaped morphology. Furthermore, due to early solidification of polymers, an incomplete phase separation and the pinning of interface also can happen.…”

Section: Resultsmentioning

confidence: 76%

One-step preparation of magnetic Janus particles using controlled phase separation of polymer blends and nanoparticles

Jeong

Park

et al. 2013

RSC Adv.

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We present a simple method with the aid of a microfluidic droplet-generation technique to fabricate magnetic Janus particles by utilizing a solvent evaporation-induced phase separation and preferential partitioning of magnetic nanoparticles in the polymer blends. Non-aqueous emulsion droplets of the polymer blends and nanoparticles solution are produced to become Janus particles after the evaporation of the solvent. The stabilizing polymer of the nanoparticles, which is compatible only with one of the polymer blends to be phase-separated, plays a key role in the anisotropic positioning of the nanoparticles in the Janus particles. Using this phase separation-based method and microfluidics, excellent control over the size, size distribution, and morphology of the particles is achieved. Especially, we could control the morphology of the Janus particles easily by varying the volume ratio of the polymers. However, with an analysis of the shapes of resulting Janus particles, we found that non-equilibrium aspects of the evaporation-induced phase separation play a major role in determining the particle morphology. We expect that the versatility of this method in the choice of polymer blends and functional nanoparticles will enable the fabrication of colloids with various functionality and desired morphology.3 Electronic supplementary information (ESI) available: Analysis of particle shapes based on thermal equilibrium assumption, including Fig. S1 and S2. See

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Janus-like polymer particles prepared via internal phase separation from emulsified polymer/oil droplets

Cited by 77 publications

References 29 publications

New insight into the mechanism of formation of dual actives loaded multilayered polymeric particles and their application in food preservation

New insight into the mechanism of formation of dual actives loaded multilayered polymeric particles and their application in food preservation

Exploration of selective decoration of Janus silica particles within polymeric patterned pore arrays

One-step preparation of magnetic Janus particles using controlled phase separation of polymer blends and nanoparticles

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