Jan Patočka - Briefe an Krzysztof Michalski

Jan, Patočka

doi:10.7761/sp.7.99

Cited by 17 publications

(20 citation statements)

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“…[9][10][11] Crystalline 30 deposits of betulin rapidly accumulate in peridermal cells during spring and nearly fill the intracellular space in summer. 12,13 The therapeutic and the pharmacological properties of betulin (and its derivatives) have intensively been investigated and properly reviewed in the last decade. 11,14 In resume, betulin exhibits a 35 wide spectrum of biological activities, such as antitumor, anti-HIV, antibacterial and anti-inflammatory properties.…”

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confidence: 99%

Microwave assisted extraction of betulin from birch outer bark

et al. 2013

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confidence: 99%

Microwave assisted extraction of betulin from birch outer bark

et al. 2013

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“…Initially, betulinic acid was considered to be melanomaspecific [9][10][11], but recent studies suggested that it shows anticancer activity against a broad spectrum of cancers [12][13][14].…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Anticancer Activity of Novel Betulinic acid and Betulin Derivatives

Kommera

Kaluđerović

Kalbitz

et al. 2010

Archiv der Pharmazie

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A series of novel betulinic acid derivatives 3-11 and betulin derivatives 12-17 were synthesized. The compounds were characterized by the means of (1)H- and (13)C-NMR spectroscopy as well as mass spectrometry. The compounds have been tested on ten tumor cell lines of different histogenic origin. The most active derivatives, containing a chloroacetyl group on C-3 in betulinic acid 9 and C-28 in betulin 15, were up to ten times more cytotoxic and many fold more selective towards tumor cells in comparison to normal cells (fibroblasts) than betulinic acid. Furthermore, compound 15 was found to possess cell growth inhibition even when treated for a short time on anaplastic thyroid cancer cells (SW1736).

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“…Thus Patočka has written: "The infl uence of the German cultural milieu on the beginnings [of national awakening] was so overpowering that it is virtually impossible to speak about a cultural distinctiveness." 71 If Herderian Romanticism laid the foundation for modern German nationalism, it performed the same role in the Czech case, which imitated the German model. In fact, we have found this view in Patočka as well.…”

Section: The Question Of a German Modelmentioning

confidence: 99%

Johann Gottfried Herder and the Czech National Awakening: A Reassessment

David¹

2007

cbp

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The Czech national awakening is habitually linked with Herder’s influence as a Romantic and anti-Enlightenment happening. This study argues the opposite. It contradicts, at least in the Czech case, the idea, originally articulated by Hans Kohn, that European nationalism, particularly in the center and the east of the continent, was an expression of a particularist self-assertion, verging on (or passing into) xenophobia, and defying the rationalistic and cosmopolitan outlook of the Enlightenment. The objective of this study is, fi rst, to show that the pace-setters of the Czech national awakening functioned within the realistic rationalist Enlightenment, rather than within the emotional self-centeredness, growing out of the Romanticist ethos. They drew on other than the Herderian sources, primarily on the Josephist Enlightenment, and the subsequent liberal Catholicism, epitomized by Karl H. Seibt and Bernard Bolzano. The assumptions to the contrary were based on (1) the allegedly anti-national character of the Enlightenment; (2) a distaste for liberal Catholicism by both the offi cial Rome and the secularists; (3) an assumption of the obvious superiority of German culture; and (4) a confusion with the Slovak national romanticism.

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Jan Patočka - Briefe an Krzysztof Michalski

Cited by 17 publications

References 0 publications

Microwave assisted extraction of betulin from birch outer bark

Microwave assisted extraction of betulin from birch outer bark

Synthesis and Anticancer Activity of Novel Betulinic acid and Betulin Derivatives

Johann Gottfried Herder and the Czech National Awakening: A Reassessment

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