Jailing polymer jacketed guide-wires during bifurcation coronary interventions is associated with procedural myocardial infarction

Abstract

AIMTo study the relationship of jailed polymer jacketed guide wires (PGW) with procedural myocardial infarction (PMI) after bifurcation coronary interventions.METHODSConsecutive bifurcation interventions performed from January 2010 to October 2014 were included in the study. Chart review was performed to obtain demographic, clinical and procedural data. PMI was defined as Creatine Kinase MB > 3 × upper reference limit of normal. Multivariate logistic regression was used to ascertain relationship of PGW use with PMI.RESULTSTwo hundred and ninety-three patients (age 63.5 ± 12.3 years; 33.8% diabetic) were included in the study. Eighty point two percent (n = 235) were true bifurcation lesions use of PGW was associated with PMI on univariate analysis (OR = 4.1; P = 0.002). This association remained significant after adjusting for other possible risk factors (OR = 3.5; P = 0.02).CONCLUSIONOur results suggest that PGW use for side branch protection may be associated with PMI. Randomized studies are needed to validate these findings.

Interventions for Left Main Coronary Artery Disease

“…Polymer-coated wires were more resistant to retrieval damage and were more efficient in crossing the SB ostium than nonpolymer-coated wires, 23 but another study reported that jailed polymerjacketed guidewires were associated with procedural MI. 24…”