Untitled

Abstract

Background: Diabetes Miletus (DM) is a serious complex condition which can affect the entire body. DM that develops during pregnancy is known as gestational diabetes (GD), which carries health risks for both the mother and fetus. Therefore, the aim of this study was to assess the possible complications among pregnant diabetic patients (cases) compared to non-diabetic pregnant ladies (controls) in Sudan. Materials and Methods:This was prospective case-control study conducted in Sudan during the period from September 2014 to March 2015. Two hundreds individuals (100 were cases and 100 were controls) were investigated using different clinical and laboratory measures.Results: Clinical complications when compared to normal pregnant women (control group), diabetic pregnant women (case group) showed significant increase in incidence of persistent glycosuria (GU), urinary tract infection (UTI), hypertension, GD in previous pregnancy, abortion / stillbirth and asymptomatic bacteriuria (AB), (P value <0.001, 0.001, 0.001, 0.001, 0.030 and 0.007 respectively). GU (98% in cases versus 1% in controls), UTI (94% in cases versus 49% in controls), hypertension (23% in cases versus 1% in controls), GDM in Previous Pregnancy (98% in cases versus none in controls), abortion / stillbirth (14% in cases versus 5% in controls) and AB (53% in cases versus 34% in controls). Conclusion:Several complications are commonly associated with pregnant diabetic patients including; glycosuria (GU), urinary tract infection (UTI), hypertension and lipid profile disorders. Pregnant diabetic ladies should undergo more medical care and follow up than non-diabetics for early management of expected complications.