Abstract:The review presents data on nonopioid action of β-endorphin and its synthetic fragment [12][13][14][15][16][17][18][19] octarphin), a selective agonist of a nonopioid β-endorphin receptor. Using tritium labeled octarphin, the receptor distribution in the body has been studied. It was discovered on immune cells (peritoneal macrophages, T and B-lymphocytes), endocrine (adrenal cortex, hypothalamus), cardiovascular (cardio myocytes) systems. Characteristics of the binding specificity showed that only unlabeled β-… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.