J. H. Campbell, artist

Thomas, Rosie

doi:10.1093/nq/cxlvii.jul19.47a

Cited by 2 publications

(3 citation statements)

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“…Male Wistar rats (12–14 weeks old) (n = 41; 5–8 rats/treatment group) were anaesthetized with isofluorane. Balloon angioplasty of LCA was performed by 3 passes of a 2 French Fogarty embolectomy catheter (Baxter, Australia) as described previously 6–8. The catheter was removed and the artery clamped above and below the site of injury, and drugs (approximately 30 μL; 10% of total dose) immediately injected into the internal carotid artery at the site of injury.…”

Section: Methodsmentioning

confidence: 99%

“…We have previously demonstrated that fibrin (including cross‐linked fibrin (XLF) and degradation product D‐dimer) rapidly accumulates at the site of vascular injury, where it can remain for many weeks 6. We used an antibody that recognizes XLF D ‐dimer to site‐deliver anti‐restenotic drugs, including low molecular weight heparin (LMWH), to the injured artery wall in rabbits.…”

mentioning

confidence: 99%

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Antibody‐Targeted Drug Delivery to Injured Arteries Using Layered Double Hydroxide Nanoparticles

Rolfe

et al. 2012

Adv Healthcare Materials

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Targeted local delivery of a nanoparticle-based, antibody-targeted, and low molecular weight heparin (LMWH) delivery system successfully reduces restenosis and thrombus formation in an animal model. An antibody recognizing cross-linked fibrin (XLF) D-dimer is successfully conjugated to layered double hydroxide nanoparticles. Use of the anti-XLF-conjugated LMWH-carrying layered double hydroxide nanoparticles shows successful targeting of the nanoparticles (red) to the injured artery wall (green), resulting in decreased neointimal thickening and thrombus formation.

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Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 99%

Antibody‐Targeted Drug Delivery to Injured Arteries Using Layered Double Hydroxide Nanoparticles

Rolfe

et al. 2012

Adv Healthcare Materials

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“…A new polyester fiber commonly referred to as PTT (or PTMT) will apparently be on the market soon. The identification characteristics are provided in this paper so the new fiber can be correctly identified by forensic and industrial microscopists (133). The characteristics of modacrylic fibers for forensic analysis has been reported and includes over 80 samples representing 15 trade names (134).…”

Section: Trace Evidencementioning

confidence: 99%