Izmir Mental Health Survey for Gene-Environment in Psychoses (TurkSch): Objectives and Methodology

Izmir Mental Health Cohort for Gene-Environment Interaction in Psychosis (TürkSch): Assessment of the Extended and Transdiagnostic Psychosis Phenotype and Analysis of Attrition in a 6-Year Follow-Up of a Community-Based Sample

“…Response was higher in older age groups and in females. Full details on the Izmir metropolitan area, sampling, representativeness, instruments, procedures of T 1 , and the map of neighborhoods included can be found in a previous article (50). Participants and addresses of T 1 formed the targeted population for T 2 .…”

“…To study gene-environment interactions when analyzing the development and course of the extended and transdiagnostic psychosis phenotype, simultaneous assessments of the genetic and the environmental factors both at the individual level and at the level of the wider social environment are required. The Izmir Mental Health Survey for Gene-Environment Interaction in Psychosis (TürkSch) was therefore conducted to provide new insights into and knowledge of the extended and transdiagnostic psychosis phenotype , and to identify social-environmental risks in interaction with genetic background (47, 49, 50).…”

Is BDNF‐Val66Met polymorphism associated with psychotic experiences and psychotic disorder outcome? Evidence from a 6 years prospective population‐based cohort study

“…The TürkSch is a prospective study consisting of several data collection stages to assess genetic and environmental factors underlying the extended psychosis phenotype in a representative general population sample. The TürkSch study was described in more detail in previous papers (Binbay, Alptekin, et al, ; Binbay, Drukker, Elbi, et al, ; Binbay et al, ). Baseline sample ( n = 4011) was randomly selected representing the wider Izmir metropolitan area (population approximately 2,650,000) (Binbay et al, ) using a multistage sampling procedure, stratified by urbanicity covering 11 districts and 302 neighborhoods.…”

“…The TürkSch study was described in more detail in previous papers (Binbay, Alptekin, et al, ; Binbay, Drukker, Elbi, et al, ; Binbay et al, ). Baseline sample ( n = 4011) was randomly selected representing the wider Izmir metropolitan area (population approximately 2,650,000) (Binbay et al, ) using a multistage sampling procedure, stratified by urbanicity covering 11 districts and 302 neighborhoods. Trained lay interviewers visited those addresses in person between November 2007 and October 2008.…”

“…In the current study, assessments included screening sections on alcohol and substance‐related disorders, depressive and dysthymic disorders, manic and bipolar affective disorders, schizophrenia and other PDs, and two final sections containing interviewer observations, and interviewer ratings. Each CIDI interview at baseline and follow‐up was conducted according to a standard procedure, with recording and quality coding (Binbay et al, ). If the quality of the interview was considered low by the team psychiatrist, a phone call or a second visit was planned.…”