2013
DOI: 10.1177/1074248413478172
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Ivabradine in Combination With Metoprolol Succinate in the Treatment of Inappropriate Sinus Tachycardia

Abstract: Combining ivabradine with metoprolol is an effective and well-tolerated treatment option for IST in patients with refractory to monotherapy.

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Cited by 46 publications
(36 citation statements)
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“…The drug has no other hemodynamic effects aside from lowering the heart rate. As such, it has been investigated for use to reduce the sinus rate and improve symptoms related to IST (85)(86)(87)(88)(89)(90)(91)(92)(93).…”
Section: Ongoing Management: Recommendationsmentioning
confidence: 99%
“…The drug has no other hemodynamic effects aside from lowering the heart rate. As such, it has been investigated for use to reduce the sinus rate and improve symptoms related to IST (85)(86)(87)(88)(89)(90)(91)(92)(93).…”
Section: Ongoing Management: Recommendationsmentioning
confidence: 99%
“…Furthermore, ivabradine can provide benefits when added to beta-blocker therapy. 64 Ivabradine is not yet available in all countries, although it might appear in the next 2–3 years.…”
Section: Section 2: Inappropriate Sinus Tachycardia Definitionmentioning
confidence: 99%
“…43,44 Ivabradine is not available in all countries but is likely to become increasingly so in the next 2-3 years. …”
Section: Treatmentmentioning
confidence: 99%