“…Macular holes result from vitreous shrink age and traction on the macula with edema, hemorrhage, exudate or degeneration due to vascular diseases, senile degeneration, trau ma, inflammation or hereditary disposition [1,5,7,9,13], In diabetic retinopathy, es pecially diabetic maculopathy, with proli ferative changes, macular holes should de velop easily. However, they have not been reported yet in the literature.…”