IV Hyperalimentation and Chemotherapy for Stage III Testicular Cancer: A Randomized Study

A.S.P.E.N. Clinical Guidelines: Nutrition Support Therapy During Adult Anticancer Treatment and in Hematopoietic Cell Transplantation

“…Several studies have examined the use of NST during chemotherapy to prevent the development of malnutrition or to mitigate its consequences. 64,[70][71][72][73][74][75][76][77][78][79][80][81][82] When used in this fashion, NST does not reduce chemotherapy-related toxicity [70][71][72][73][74][75]77,78,80,81 and does not improve tumor response [70][71][72][73][74][75]77,78,80,81 or patient survival. 70,71,75 All studies were limited by small sample size.…”

Nutritional support of the cancer patient

“…Several randomized studies using different chemotherapeutic protocols to treat various types of cancer have addressed this issue 58,64–66 . The results of these studies showed that TPN did not confer an advantage in decreasing chemotherapy‐induced morbidity or tumor responsiveness.…”

Parenteral Nutrition Support in Patients With Cancer

“…Studies performed in patients with lung cancer, lymphoma, testis cancer, and sarcoma demonstrated no differences in response or survival between patients who did and those who did not receive TPN. [39][40][41][42][43] Some studies in patients with lung cancer even revealed decreased survival and response rate^.^'^^^ Of note, three of six studies reported significantly more mucositis in TPN-treated patients. A meta-analysis demonstrated that the odds ratio for increased infectious complications was increased 4-fold in patients receiving TPN.…”