IUGR Management: New Perspectives

Giuliano, Natascia; Annunziata, Maria Laura; Tagliaferri, Salvatore; Esposito, Francesca; Imperato, Olga Carmela Maria; Campanile, Marta; Signorini, M.G.; Lieto, Andrea Di

doi:10.1155/2014/620976

Cited by 9 publications

(9 citation statements)

References 64 publications

(74 reference statements)

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“…This is consistent with previous studies in which the prevalence of severe hypertension and preeclampsia was 43% , much higher than the 5% prevalence of preeclampsia usually observed in the general population . Consistent with this, low birth weight and intrauterine growth restriction were reported in up to 20% of pregnancies in TAK patients compared to 5–8% in the general population . In contrast to the findings of Suri et al , we did not observe a higher rate of preeclampsia and intrauterine growth restriction in patients with abdominal aorta and renal artery involvement.…”

Section: Discussionsupporting

confidence: 91%

Takayasu Arteritis and Pregnancy

Comarmond

Mirault

Biard

et al. 2015

Arthritis & Rheumatology

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Objective. To assess the relationship between Takayasu arteritis (TAK) and pregnancy outcome.Methods. This study included 240 pregnancies in 96 patients fulfilling the American College of Rheumatology 1990 criteria for the classification of TAK and/or the 1994 Chapel Hill Consensus Conference nomenclature/criteria for vasculitis. We analyzed obstetric and maternal outcomes in women who were pregnant before and/or at the same time as or after TAK diagnosis. We assessed factors associated with complicated pregnancy.Results. Conclusion. TAK negatively affects pregnancy outcomes. Disease activity increases the risk of obstetric and maternal complications, mainly due to arterial hypertension.Takayasu arteritis (TAK) is a chronic inflammatory vasculitis of unknown origin affecting large vessels, predominantly the aorta and its main branches (1). Vessel inflammation leads to wall thickening, fibrosis, stenosis, and thrombus formation. More acute inflammation can severely compromise the arterial media, leading to loss of vessel wall integrity and aneurysm formation. These lesions are often asymptomatic unless they dissect, rupture, or, in the case of the aorta, produce root/arch aneurysms and aortic regurgitation. These lesions are often discovered after many years of disease. Symptoms reflect end-organ ischemia. During TAK, cardiovascular events are not uncommon (2,3). Pregnancy can also lead to vascular injury, and pregnancy-related cardiovascular and cerebrovascular accidents are feared maternal complications. Cardiovascular and cerebrovascular events account for 5-19% of all maternal deaths during pregnancy (4).

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Section: Discussionsupporting

confidence: 91%

Takayasu Arteritis and Pregnancy

Comarmond

Mirault

Biard

et al. 2015

Arthritis & Rheumatology

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“…Possible reasons include the following: First, fetal hypoxic injuries may vary in the target organs most affected and timing of deterioration, which is why the combination of different fetal parameters continues to be the best model at this point. The authors of the TRUFFLE study emphasized that despite the fact that absent/reversed DV a‐wave velocity has been considered the best predictor of normal infant neurodevelopment in severe IUGR, its use in clinical practice should be correlated with other biophysical variables, mostly using computerized cardiotocography (cCTG). As cCTG is not available at units participating in this study, the role of this method was not addressed.…”

Section: Discussionmentioning

confidence: 99%

Predictors of perinatal outcome in early‐onset fetal growth restriction: A study from an emerging economy country

et al. 2020

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What's already known about this topic? The use of fetal arterial and venous Doppler studies is well acknowledged in the context of fetal growth restriction, with ductus venosus evaluation as the most correlated with fetal acidosis and impending risk of death. What does this study add? In a subpopulation of severely growth‐restricted fetuses, the use of z‐score instead of gestational age or fetal weight alone may perform better in a prediction model including biometric and Doppler variables.

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“…IUGR defined when the fetal weight below the 10 th percentile for gestational age, and diagnosed by trans-abdominal ultrasound (TAS) [18]. Scifres et al,…”

Section: Methodsmentioning

confidence: 99%

Diagnostic Accuracy of PremaQuick versus Actim Partus in Prediction of Preterm Labor in Symptomatic Women within 14 Days

Abu-Faza¹,

Abdelazim²,

Svetlana³

et al. 2018

OJOG

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Background: Preterm labor (PTL) remains a major source of neonatal morbidity, and mortality. Currently the trans-vaginal cervical length (TVCL), and/or cervico-vaginal fetal fibronectin (fFN) are the common diagnostic tools used for prediction of PTL. Consequently, many women and their fetuses are exposed unnecessarily tocolysis and hospital admission. Objectives: This study was designed to compare the diagnostic accuracy of PremaQuick versus Actim Partus in prediction of PTL in symptomatic women within 14 days. Patients and Methods: Two-hundred and twenty women (220) were included in this comparative prospective study and classified into two groups: 110 women with threatened preterm labor (TPTL) in the study group, and 110 controls (no TPTL). Women included in the study were subjected to: through history, collection of the cervico-vaginal fluid (CVF) samples for assessment by PremaQuick and Actim Partus tests, followed by trans-vaginal cervical length (TVCL) assessment. Studied women managed according to the hospitals protocol, with follow-up weekly in the obstetrics outpatients' clinic after discharge from the hospital until delivery. The main outcome measures the diagnostic accuracy of PremaQuick versus Actim Partus in prediction of PTL in symptomatic women within 14 days of admission. Results: PremaQuick test was significantly more specific with higher positive predictive value (PPV) in prediction of PTL in symptomatic women within 14 days (95.5% and 89.6%; respectively) compared to CL < 25 mm (56.3% and 54.6%; 742 Open Journal of Obstetrics and Gynecology respectively), (P = 0.02 and 0.03; respectively). In addition, PremaQuick test was significantly more sensitive with higher positive predictive value (PPV) in prediction of PTL in symptomatic women within 14 days (39.8% and 89.6%; respectively) compared to Actim Partus (13.9% and 55.5%; respectively), (P = 0.001 and 0.01; respectively). The Odds ratio and the relative risk for prediction of PTL in symptomatic women within 14 days were significantly high for PremaQuick compared to the CL < 25 mm, and Actim Partus. Conclusion: PremaQuick test seems to be the best complementary test to the CL < 25 in prediction of PTL in symptomatic women within 14 days. PremaQuick test compensates the low specificity and low PPV of the CL < 25 mm in prediction of PTL.

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IUGR Management: New Perspectives

Cited by 9 publications

References 64 publications

Takayasu Arteritis and Pregnancy

Takayasu Arteritis and Pregnancy

Predictors of perinatal outcome in early‐onset fetal growth restriction: A study from an emerging economy country

Diagnostic Accuracy of PremaQuick versus Actim Partus in Prediction of Preterm Labor in Symptomatic Women within 14 Days

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