Itraconazole as a new pharmacotherapy method in haemangiomas

Malassezia infection associated with stucco keratosis

“…Of course, it is worth debating whether systemic administration of itraconazole and hydroxychloroquine resulted in the elimination of this benign tumor by inhibiting Malassezia . As a classic systemic triazole antifungal drug, itraconazole has been confirmed to inhibit angiogenesis and proliferation while leading to increased apoptosis, thus expanding its new role in the treatment of hemangioma and non-small cell lung cancer [ [9] , [10] , [11] , [12] ]. However, no inhibitory effect of itraconazole on the proliferation of keratinocytes has been found so far.…”