iTClamp-Mediated Wound Closure Speeds Control of Arterial Hemorrhage With or Without Additional Hemostatic Agents

Stuart, Sean; Bohan, Megan L; McLean, Julie; Walchak, Alexandra C; Friedrich, Emily E.

doi:10.55460/tpmg-0mqu

Cited by 2 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Preclinical studies of severe bleeding provide evidence that the iTClamp in addition to wound packing can significantly reduce blood loss. 54,55 This approach is also particularly effective for penetrating neck injuries and is recommended for hemostatic management of craniofacial and neck injuries. 56,57 Injectable self-expanding gauzes for narrow-tract wounds (Xstat, RevMedx, Wilsonville, OR) or those containing coagulation pathway activators including kaolin (Combat Gauze, Teleflex, Morrisville, NC) or chitosan-induced red cell aggregation (Celox Gauze, Medtrade Products Ltd, Crewe, United Kingdom) are also useful adjuncts for use in difficult to access wounds or when compression may be limited due to anatomy or microgravity.…”

Section: Applying Lessons Learned For Managing Hemostasis On Earth An...mentioning

confidence: 99%

Managing Hemostasis in Space

White,

Wenthe

2023

ATVB

View full text Add to dashboard Cite

Human space travel requires exposure to weightlessness, ionizing radiation, isolation, and austerity. A recent report of internal jugular vein thrombosis in astronauts in low Earth orbit confirms that these exposures also affect vascular biology to influence diseases of thrombosis and hemostasis. This brief review summarizes the known influences of space travel on inflammation, blood coagulation, and the cardiovascular system and conceptualizes how they might combine to affect thrombosis and hemostasis. In the event of a major thrombotic or bleeding emergency, it is anticipated that the unique physiological influences of the space environment and logistical limitations of providing medical care in space would require a response that is unique from our current experience. We also look towards the future to discuss lessons learned from our current experiences on Earth and in space.

show abstract

Section: Applying Lessons Learned For Managing Hemostasis On Earth An...mentioning

confidence: 99%

Managing Hemostasis in Space

White,

Wenthe

2023

ATVB

View full text Add to dashboard Cite

show abstract

Speed, Skill Retention, and End User Perceptions of iTClamp Application by Navy Corpsmen on a Manikin Model of Femoral Hemorrhage

2022

View full text Add to dashboard Cite

Introduction Tactical Combat Casualty Care guidelines recommend packing junctional wounds with gauze, applying direct pressure for 3 minutes, and then securing with an external pressure dressing. This method is time-consuming, which can be problematic in a combat environment. Alternatively, the iTClamp has documented efficacy and rapid application. However, no studies have evaluated device application by military prehospital medical providers, such as Navy corpsmen, or their user experience with the device. Materials and Methods Research data derived from a protocol were approved by the Naval Medical Center Portsmouth’s Institutional Review Board in compliance with all applicable federal regulations governing the protection of human subjects. Navy corpsmen with the current Tactical Combat Casualty Care certification applied the iTClamp or standard pressure dressing on a manikin model of femoral hemorrhage in a crossover study design. Each participant used both devices in a randomized fashion. Time to application was recorded, and participants completed Likert scale surveys to evaluate both devices for preference, ease of use, and physical assessment. A repeat assessment was performed 1 month later to assess skill atrophy. Repeated-measures ANOVA was used to compare application time. Likert scale survey data were analyzed using Mann–Whitney and Wilcoxon tests to compare survey data within and between time points, respectively. Results The application of the iTClamp was more than twice as fast as the application of pressure dressings at both the initial and follow-up evaluations. There was no statistically significant difference in application times between the first evaluation and the 30-day assessment of either device, indicating no atrophy in skill. While 65% and 52% of the participants expressed preference in for the iTClamp in their surveys during the initial and follow-up respective visits, the difference in preference was not statistically significant for either the initial or the follow-up survey. Open-ended survey responses yielded both perceived advantages and disadvantages for each treatment option. Conclusions In austere or hostile environments, speed of treatment and extrication can have significant implications for the safety of both the patient and the medical providers. Hemorrhage control interventions must be both effective and easy to use for a prehospital provider to ensure its efficacy in a live battlefield situation. The iTClamp is small, simple, and fast to use, but its wide adoption in the field may be based on limitations perceived by participants, including narrow indications for use. However, based on our findings, it is reasonable to field the iTClamp depending on provider preference.

show abstract

iTClamp-Mediated Wound Closure Speeds Control of Arterial Hemorrhage With or Without Additional Hemostatic Agents

Cited by 2 publications

References 0 publications

Managing Hemostasis in Space

Managing Hemostasis in Space

Speed, Skill Retention, and End User Perceptions of iTClamp Application by Navy Corpsmen on a Manikin Model of Femoral Hemorrhage

Contact Info

Product

Resources

About