Itching and its related factors in subtypes of eczema: a cross-sectional multicenter study in tertiary hospitals of China

Abstract

Itching is a leading symptom of eczema or dermatitis and has a great impact on patients’ lives. Previous studies on itching have focused mostly on atopic dermatitis (AD). A cross-sectional multicenter study was conducted among outpatients with eczema from 39 tertiary hospitals in mainland China from July 1 to September 30, 2014. This work elaborates on itching in different types of eczema. Itching was very common (97%, 8499/8758) in outpatients with eczema. The severity of the itch increased with age and disease duration (P < 0.001). The top three subtypes of dermatitis with severe itching were atopic dermatitis (30.4%), widespread eczema (30.1%), and asteatotic eczema (27.9%). Widespread eczema refers to the involvement of more than three body parts, without clinical features of other specific types of eczema. The proportion of outpatients without itching was highest in hand eczema (6.8%). Positive correlations were observed between the severity of itching and the proportions of different diseases based on trend tests, including atopic dermatitis (P < 0.001), widespread eczema (P < 0.001), asteatotic eczema (P < 0.001), and autosensitization dermatitis (P < 0.001). Eczema outpatients with older age, longer disease duration, and, especially, a history of allergic diseases might be more prone to itching.

Real‐world prevalence and burden of genital eczema in atopic dermatitis: A multicenter questionnaire‐based study

“…14 In addition, the severity of pain in patients with genital eczema was also higher than that in those with hand eczema (mean VAS, 2.6 ± 3.0). 14 Moreover, the study by Wang et al 15 found that 11.5% of patients with hand eczema and 6.9% of patients with seborrheic dermatitis suffered from severe pruritus, while a higher proportion of severe pruritus in patients with genital eczema (22.22%) was observed in this study. Concerning DLQI, patients with genital eczema showed a poorer QOL than patients without genital eczema overall.…”

Autoeczematization: A Strange Id Reaction of the Skin

“…The pruritus may be so intense that it interrupts daily activities and disrupts the ability to fall or stay asleep. 16 Histologically, biopsy specimens show psoriasiform spongiotic dermatitis with mononuclear cells contained in the vesicles. Interstitial edema and perivascular lymphohistiocytic infiltrates are evident.…”

Risk Factors in Outpatients with Dermatitis and Eczema in Tertiary Hospitals of China Who Have Clinically Suspected Bacterial Infection

“…In this study, atopic dermatitis was diagnosed according to the Williams diagnostic criteria [10]. Widespread eczema refers to the presence of eczema at multiple sites at the same time [11,12].Other types of eczema, including allergic contact dermatitis, asteatotic eczema, autosensitization eczema, dyshidrotic eczema, hand eczema, irritant contact dermatitis, neurodermatitis, nummular eczema, photocontact dermatitis, seborrheic dermatitis, stasis dermatitis, unclassified eczema, and widespread eczema, were diagnosed on the basis of clinical characteristics and medical history according to the International Classification of Diseases-(ICD-) 10 [13][14][15]. Suspected secondary bacterial infection of dermatitis was clinically evaluated.…”