Italian Biological Prosthesis Work-Group (IBPWG): proposal for a decisional model in using biological prosthesis

Catena, Fausto; Agresta, Ferdinando; Bassi, Andrea; Catena, Fausto; Crovella, Feliciano; Ferrara, Roberto; Gossetti, Francesco; Marchi, Domenico; Munegato, Gabriele; Negro, Paolo; Piccoli, Micaela; Melotti, Gianluigi; Sartelli, Massimo; Visconte, Michele Schiano di; Testini, Mario; Bertoli, Paolo; Capponi, M; Lotti, Marco; Manfredi, Roberto; Pisano, Michele; Poiasina, Elia; Poletti, Eugenio; Ansaloni, Luca

doi:10.1186/1749-7922-7-34

Cited by 40 publications

(31 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This did however not work despite huge efforts, and this is currently not being used. In Italy, the Italian Biological Prosthesis Work-Group (IBPWG) was established and has published its results from 264 biological implants in Italy [33]. A scoring system was developed, with the purpose to help the surgeon to choose between cross-linked and non-crosslinked BM.…”

Section: Registersmentioning

confidence: 99%

The battle between biological and synthetic meshes in ventral hernia repair

Montgomery

2013

Hernia

View full text Add to dashboard Cite

Section: Registersmentioning

confidence: 99%

The battle between biological and synthetic meshes in ventral hernia repair

Montgomery

2013

Hernia

View full text Add to dashboard Cite

“…On the contrary, BP activate a remodeling process guiding the host to start a real tissue engineering process [126]. The correct use of different BP in abdominal wall surgery, and ventral/ incisional hernia in particular, remains unclear [120,127].…”

Section: Luca Ansalonimentioning

confidence: 99%

Laparoscopic ventral/incisional hernia repair: updated guidelines from the EAES and EHS endorsed Consensus Development Conference

et al. 2015

Self Cite

View full text Add to dashboard Cite

The availability of recent level 1 evidence (a meta-analysis of 10 RCTs) allowed to recommend that not only laparoscopic repair is an acceptable alternative to the open repair, but also it is advantageous in terms of shorter hospital stay and wound infection rate. This conclusion appears to be extremely relevant in a clinical setting. Indications about specific conditions could also be issued: laparoscopy is recommended for the treatment of recurrent ventral hernias and obese patients, while it is a potential option for compensated cirrhotic and childbearing-age female patients. Many relevant and controversial topics were thoroughly examined by this consensus conference for the first time. Among them are the issue of safety of the intraperitoneal mesh placement, traditionally considered a major drawback of the laparoscopic technique, the role for the biologic meshes, and various aspects of the laparoscopic approach for particular locations of the defect such as the abdominal border or parastomal hernias.

show abstract

“…The proposal of a decisional model to apply BPs has already been published elsewhere [23] by the Italian Biological Prosthesis Work Group. However, without high evidence level clinical data, all the indications will be experience based.…”

Section: Discussionmentioning

confidence: 99%

“…The different degrees of contamination increase the surgical field's infection risk. In this setting, a BP would be a good choice [23]. …”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

The Italian Register of Biological Prostheses

Catena

Bertoli²,

Gossetti³

et al. 2013

Eur Surg Res

View full text Add to dashboard Cite

Background: A wide variety of meshes are available for surgical treatment of abdominal wall defects. These meshes are constructed with different materials with different biological properties. Methods: A prospective database was instituted (January 2009-December 2010) to register biological prostheses (BPs) implanted in Italy. Results: A total of 193 cases were registered. The mean age of the patients was 53.1 years (SD ±7.4). The ratio of males to females was 1.3 to 1. The mean body mass index was 28.2 (SD ±4.1). The breakdown of American Society of Anesthesiologists (ASA) scores was as follows: ASA I, 35.7%; ASA II, 27.5%; ASA III, 31.6%, and ASA IV, 5.2%. For ventral-incisional hernias, the mean duration of surgery was 101.1 min (SD ±25.3), while for inguinal-femoral hernias it was 49.2 min (SD ±19.1). The rate of urgent procedures was 36.7%. The surgical field was clean in 57.4% of cases, clean-contaminated in 21.3%, contaminated in 12.3% and dirty in 9%. Techniques used for inguinal-femoral hernias were as follows: Lichtenstein in 66.7%, plug and mesh in 3.8%, transabdominal-preperitoneal in 25.7% and intraperitoneal onlay mesh in 3.8%. The following prostheses were used: swine intestinal submucosa in 54.9%, porcine dermal collagen in 39.9% and bovine pericardium in 5.2%. In 45.1% of cases the prostheses were cross-linked. Techniques used for ventral-incisional hernias were as follows: onlay in 3.6%, inlay in 5.5%, sublay in 62.7% and underlay via laparoscopy in 28.2%. The mean overlap was 4.1 cm (SD ±1.2). No intestinal anastomosis was necessary in 65.3% of cases; however, small/large bowel resection and anastomoses were necessary in 22.3 and 12.4% of cases, respectively. Intraoperative blood transfusion was necessary in 10.4% of procedures. The skin was completely closed in 84% of procedures. At the 1-month follow-up, there were no complications in 54.4% of cases. Among the cases with complications, 10 patients (5.8%) experienced recurrence, and the postoperative readmission rate was 12.9%. The average visual analog scale (VAS) score for pain was 2.9 (SD ±1.2) at rest. At the 1-year follow-up, there were no complications in 96.4% of cases. Two patients experienced recurrence, and the postoperative readmission rate was 3.6%. The average VAS score for pain was 1.8 (SD ±0.8) at rest. Conclusions: This register shows that BPs are highly versatile and can be used in either open or laparoscopic surgery in all kinds of patients and in contaminated surgical fields. However, due to the very good outcomes of synthetic meshes and the high costs of BPs, the latter should only be used in selected cases.

show abstract

Italian Biological Prosthesis Work-Group (IBPWG): proposal for a decisional model in using biological prosthesis

Cited by 40 publications

References 20 publications

The battle between biological and synthetic meshes in ventral hernia repair

The battle between biological and synthetic meshes in ventral hernia repair

Laparoscopic ventral/incisional hernia repair: updated guidelines from the EAES and EHS endorsed Consensus Development Conference

The Italian Register of Biological Prostheses

Contact Info

Product

Resources

About