2023
DOI: 10.1111/cod.14359
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It is not always chlorhexidine: Identification of benzoxonium chloride and lauramine oxide as culprit allergens in a popular antiseptic in Switzerland

Abstract: BackgroundA popular antiseptic spray in Switzerland (Merfen spray), containing chlorhexidine digluconate, benzoxonium chloride and lauramine oxide, is frequently used to treat skin wounds. However, it is also increasingly reported as a major cause of adverse skin reactions, including allergic contact dermatitis (ACD).ObjectivesTo investigate the contact allergens responsible for ACD from this antiseptic.Patients/MethodsPatch tests were performed on seven patients with a clinical history compatible with contact… Show more

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