Issues of Antibiotic Resistance in Aquaculture Industry and  Its Way Forward

Aich, Nilav; Ahmed, Nazir; Paul, Anirban

doi:10.20546/ijcmas.2018.708.004

Cited by 13 publications

(14 citation statements)

References 51 publications

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“…Consequently, antibiotics usage for both therapeutic and nontherapeutic purposes is dramatically increasing. Sulfonamides, penicillins, quinolones, tetracyclines, and phenicols are the antibiotic classes of most concern and their extensive usage is yet associated with a significant contribution to the overall spread of AMR between all animal species, humans included [60,61].…”

Section: Aquaculture and Amrmentioning

confidence: 99%

“…This unavoidably leads to the customary employment of antimicrobials for both prophylactic and therapeutic purposes, resulting in a strong selective pressure that favors the emergence and selection of AMR strains, and the subsequent dissemination of the AMR traits through mobilizable elements via various routes (food, feed, environment) [60,[63][64][65]. To date, no antibiotics have been specifically designed for the exclusive use in aquaculture; thus, antimicrobial compounds destined to other sectors of the human and veterinary medicine are improperly used in the aquaculture context, enhancing dramatically the impact of AMR onset and diffusion [60,61]. Six of the antibiotic classes listed by the World Health Organization (WHO) as critically important for human medicine (aminoglycosides, macrolides, penicillins, quinolones, sulphonamides, and tetracyclines) are commonly employed in both terrestrial and aquaculture husbandries, resulting in an enormous contribution to the reduced efficacy of such compounds in the treatment of human-relevant infections [60,61,66,67].…”

Section: Aquaculture and Amrmentioning

confidence: 99%

“…To date, no antibiotics have been specifically designed for the exclusive use in aquaculture; thus, antimicrobial compounds destined to other sectors of the human and veterinary medicine are improperly used in the aquaculture context, enhancing dramatically the impact of AMR onset and diffusion [60,61]. Six of the antibiotic classes listed by the World Health Organization (WHO) as critically important for human medicine (aminoglycosides, macrolides, penicillins, quinolones, sulphonamides, and tetracyclines) are commonly employed in both terrestrial and aquaculture husbandries, resulting in an enormous contribution to the reduced efficacy of such compounds in the treatment of human-relevant infections [60,61,66,67]. Furthermore, inadequate usage of antibiotics is associated with a reduced capability of the fish species to effectively metabolize the administered drugs.…”

Section: Aquaculture and Amrmentioning

confidence: 99%

See 2 more Smart Citations

Antimicrobial Resistance in Veterinary Medicine: An Overview

Palma

Tilocca

Roncada

2020

IJMS

168

100

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Antimicrobial resistance (AMR) represents one of the most important human- and animal health-threatening issues worldwide. Bacterial capability to face antimicrobial compounds is an ancient feature, enabling bacterial survival over time and the dynamic surrounding. Moreover, bacteria make use of their evolutionary machinery to adapt to the selective pressure exerted by antibiotic treatments, resulting in reduced efficacy of the therapeutic intervention against human and animal infections. The mechanisms responsible for both innate and acquired AMR are thoroughly investigated. Commonly, AMR traits are included in mobilizable genetic elements enabling the homogeneous diffusion of the AMR traits pool between the ecosystems of diverse sectors, such as human medicine, veterinary medicine, and the environment. Thus, a coordinated multisectoral approach, such as One-Health, provides a detailed comprehensive picture of the AMR onset and diffusion. Following a general revision of the molecular mechanisms responsible for both innate and acquired AMR, the present manuscript focuses on reviewing the contribution of veterinary medicine to the overall issue of AMR. The main sources of AMR amenable to veterinary medicine are described, driving the attention towards the indissoluble cross-talk existing between the diverse ecosystems and sectors and their cumulative cooperation to this warning phenomenon.

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Section: Aquaculture and Amrmentioning

confidence: 99%

Section: Aquaculture and Amrmentioning

confidence: 99%

Section: Aquaculture and Amrmentioning

confidence: 99%

See 1 more Smart Citation

Antimicrobial Resistance in Veterinary Medicine: An Overview

Palma

Tilocca

Roncada

2020

IJMS

168

100

View full text Add to dashboard Cite

show abstract

“…The intensive use of antimicrobials in aquaculture to combat diseases provides a selective pressure creating reservoirs Indian Journal of Animal Health, Special Issue, December, 2019 of drug-resistant bacteria and transferable resistance genes in fish pathogens and other bacteria in the aquatic environment (Romero et al, 2012). Various authors have emphasized the putative negative effects of using antimicrobial agents in fish farms (Romero et al, 2012;Watts et al, 2017;Aich et al, 2018). Motile aeromonads remain the most dominant group isolated from aquatic environments due to its omnipresence.…”

Section: Antimicrobial Resistance In Motile Aeromonads Of Aquaculture Environmentmentioning

confidence: 99%

Emergence and spread of antimicrobial resistance in motile aeromonads of the aquaculture environment

Abraham¹,

Bardhan²

2019

ijah

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The global rise in antimicrobial resistance (AMR) among bacteria causing infectious diseases and the associated risks on human health are well known. The uproar of AMR has provided with the most severe health threat of the century. The research on the AMR of the organisms present in the environment is, however, meagre. The bacterial species of the genus Aeromonas is widely distributed in the environment that comprises both motile and non-motile variants. Several of them are autochthonous to the aquatic environment. The motile aeromonads, in particular, are notorious and contribute to severe health hazards to the humans and aquatic animals. In a variety of fish, they cause motile Aeromonas septicemia (MAS). Immunosuppressive events like nutritional, environmental and handling stress may trigger MAS. Different groups of antibiotics are used in the treatment of human and animal diseases and the indiscriminate use of which leads to disturbing consequences of AMR. Much of the susceptibility information available on the genus Aeromonas are based solely upon three major species associated with human diseases. It is not entirely clear whether those patterns can be extrapolated to other less frequently encountered taxa causing illness. In recent years, the emergence of AMR among the motile aeromonads of fish demonstrated the abuse of antibiotics in aquaculture. In this review, the AMR among motile aeromonads of the aquaculture environment and their mitigation are discussed. The available data indicated that the opportunistic pathogens like motile aeromonads might serve as important vectors of AMR in the aquatic environment.

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“…These strains could be an important causative agent of epizootic diseases in fish, other wild animals, livestock and, consequently, humans [3][4][5]. Higher concentrations of potentially pathogenic strains in water bodies increases the risk of infection for aquatic organisms and contributes to their spread not only in aquatic ecosystems, but also among humans, livestock and wildlife [6,7].…”

Section: Introductionmentioning

confidence: 99%

The Influence of Aquaculture Effluents on the Prevalence and Biocides Resistance of Opportunistic Pseudomonas fluorescens Bacteria in the Drwęca River Protected under the Natura 2000 Network

Gołaś

2020

Water

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The aim of this study was to determine the effect of trout aquaculture effluents on the Drwęca River. The count of opportunistic pathogen Pseudomonas fluorescens (OPPF) in the total Pseudomonas fluorescens population (TPFP) were determined by plating on King B medium and fluorescence in situ hybridization. The resistance of OPPF strains to 12 antibiotics and two disinfectants was evaluated. Significant differences (p ≤ 0.05) in OPPF counts were found between seven sampling sites. OPPF counts were highest in samples collected directly downstream from three fish farms. More than 50% of these isolates demonstrated multiple-drug resistance to ampicillin, mezlocillin, cefotaxime, norfloxacin, tetracycline and two disinfectants (Steridial and chloramine T). Of these, 52% were resistant to high doses of cefotaxime and norfloxacin (MIC ≥ 256 µg·mL−1), and 65% were resistant to the maximum doses of Steridial (MIC Ste ≥ 25 mL·m−3) and chloramine T (MIC Chlor ≥ 20 mg·L−1). All OPPF sampled upstream from the farms were sensitive to low concentrations of CTX (cefotaxime) and NOR (norfloxacin) (MIC ≤ 2 µg·mL−1), Steridial (MIC Ste ≤ 5 mL·m−3) and chloramine T (MIC Chlor ≤ 2.5 mg·L−1). Agglomerative clustering revealed two clusters: strains from samples collected upstream and downstream from trout farms. The results indicate that aquaculture effluents significantly affect the prevalence of biocides resistant OPPF along the river continuum.

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Issues of Antibiotic Resistance in Aquaculture Industry and Its Way Forward

Cited by 13 publications

References 51 publications

Antimicrobial Resistance in Veterinary Medicine: An Overview

Antimicrobial Resistance in Veterinary Medicine: An Overview

Emergence and spread of antimicrobial resistance in motile aeromonads of the aquaculture environment

The Influence of Aquaculture Effluents on the Prevalence and Biocides Resistance of Opportunistic Pseudomonas fluorescens Bacteria in the Drwęca River Protected under the Natura 2000 Network

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