2006
DOI: 10.1016/j.neuro.2005.10.010
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Issues in neurological risk assessment for occupational exposures: The Bay Bridge welders

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Cited by 38 publications
(35 citation statements)
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“…5,7,8 In a recent study of 351 welders, more than half had "taste" problems, although no chemosensory testing was performed and no distinction was made between flavor sensations dependent on the sense of smell and those dependent on the sense of taste. 3 In the present study, a component of the San Francisco/Oakland Bay Bridge Welder Study, 9,10,11 we quantitatively evaluated the olfactory function of professional welders who worked in confined spaces on the Bay Bridge, and compared their test scores with those of matched normal controls. These scores were also correlated with those from a number of neurologic, neuropsychological, and physiologic (e.g., blood levels of Mn, Fe, Cu, and Pb) measures.…”
mentioning
confidence: 99%
“…5,7,8 In a recent study of 351 welders, more than half had "taste" problems, although no chemosensory testing was performed and no distinction was made between flavor sensations dependent on the sense of smell and those dependent on the sense of taste. 3 In the present study, a component of the San Francisco/Oakland Bay Bridge Welder Study, 9,10,11 we quantitatively evaluated the olfactory function of professional welders who worked in confined spaces on the Bay Bridge, and compared their test scores with those of matched normal controls. These scores were also correlated with those from a number of neurologic, neuropsychological, and physiologic (e.g., blood levels of Mn, Fe, Cu, and Pb) measures.…”
mentioning
confidence: 99%
“…In other words, the lack of an FIGURE 2. Association between cumulative air Mn exposure index (CEI) and blood (A), plasma (B), and urine (C) Mn levels in Bay Bridge welders (see Park et al [2006] and Bowler et al [2007] association between air and blood Mn in the high exposure group may reflect both the variable nature of the exposure, and the fact that there may be a contribution from endogenous Mn accumulated from past exposures.…”
Section: Occupational Studiesmentioning
confidence: 99%
“…For example, chronic exposure to Mn can lead to increased susceptibility toward developing pulmonary infections including pneumonia and bronchitis (Baader 1932;Davies and Harding 1949;Rodier 1955;Maigetter et al 1976;Bencko and Cikrt 1984;Roels et al 1987;Saric 1992;Saric and Piasek 2000;Jafari and Assari 2004;Bowler et al 2007;Antonini et al 2009). Similarly, hearing deficits have also been reported in occupations in which individuals are exposed to chronic high levels of Mn (Nikolov 1974;Khalkova and Kostadinova 1986;Korczynski 2000;Josephs et al 2005;Park et al 2006;Da Silva et al 2007;Vezér et al 2007;Bouchard et al 2008). Although Mn readily accumulates in both the lung and inner ear (Kalliomäki et al 1983;Park et al 2007;Ma et al 2008), few studies have actually attempted to characterize the specific biochemical and molecular mechanisms leading to malfunction in these organs.…”
Section: Introductionmentioning
confidence: 98%